$417 Cheap Flights from Key West (EYW) to Santiago (STI)

View $417 flight on Mon, Mar 16, 2026Opens in a new window

Popular airlines from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI)

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Cheap Flights from Key West to Santiago (EYW-STI)

Prices were available within the past 7 days and start at $417 for one-way flights and $582 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Nov 13 - Fri, Nov 14
EYW
Key West
STI
Santiago de los Caballeros
$582 Roundtrip, found 1 day ago
$582
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Nov 13 from Key West to Santiago de los Caballeros, returning Fri, Nov 14, priced at $582 found 1 day ago
American Airlines
Wed, Dec 24 - Tue, Jan 6
EYW
Key West
STI
Santiago de los Caballeros
$590 Roundtrip, found 5 days ago
$590
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Dec 24 from Key West to Santiago de los Caballeros, returning Tue, Jan 6, priced at $590 found 5 days ago
American Airlines
Wed, Dec 24 - Tue, Jan 6
EYW
Key West
STI
Santiago de los Caballeros
$600 Roundtrip, found 5 days ago
$600
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Dec 24 from Key West to Santiago de los Caballeros, returning Tue, Jan 6, priced at $600 found 5 days ago
Delta
Wed, Nov 12 - Fri, Nov 14
EYW
Key West
STI
Santiago de los Caballeros
$632 Roundtrip, found 1 day ago
$632
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Nov 12 from Key West to Santiago de los Caballeros, returning Fri, Nov 14, priced at $632 found 1 day ago
American Airlines
Mon, Mar 16 - Fri, Mar 27
EYW
Key West
STI
Santiago de los Caballeros
$646 Roundtrip, found 6 days ago
$646
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Mar 16 from Key West to Santiago de los Caballeros, returning Fri, Mar 27, priced at $646 found 6 days ago
American Airlines
Mon, Mar 16 - Fri, Mar 27
EYW
Key West
STI
Santiago de los Caballeros
$653 Roundtrip, found 6 days ago
$653
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Mar 16 from Key West to Santiago de los Caballeros, returning Fri, Mar 27, priced at $653 found 6 days ago
American Airlines
Wed, Dec 24 - Tue, Jan 6
EYW
Key West
STI
Santiago de los Caballeros
$655 Roundtrip, found 5 days ago
$655
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Dec 24 from Key West to Santiago de los Caballeros, returning Tue, Jan 6, priced at $655 found 5 days ago
American Airlines
Wed, Dec 24 - Tue, Jan 6
EYW
Key West
STI
Santiago de los Caballeros
$663 Roundtrip, found 5 days ago
$663
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Dec 24 from Key West to Santiago de los Caballeros, returning Tue, Jan 6, priced at $663 found 5 days ago
American Airlines
Wed, Dec 24 - Tue, Jan 6
EYW
Key West
STI
Santiago de los Caballeros
$672 Roundtrip, found 5 days ago
$672
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Dec 24 from Key West to Santiago de los Caballeros, returning Tue, Jan 6, priced at $672 found 5 days ago
Delta
Sat, Nov 8 - Tue, Nov 11
EYW
Key West
STI
Santiago de los Caballeros
$672 Roundtrip, found 1 day ago
$672
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Nov 8 from Key West to Santiago de los Caballeros, returning Tue, Nov 11, priced at $672 found 1 day ago

Alternative airports near Santiago de los Caballeros

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Cibao Intl. STI. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $632
STI
Cibao Intl.
CheapestClosest
Average driving time to city center17 min
Flights from $632

Frequently asked questions

How much does a flight from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI) cost?
Get a cheap one-way flight from $417 or cheap return flight from $582 from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI)?
Planning your trip for November is a good way to save, as it's the cheapest month for flights between EYW and STI. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest EYW to STI flight.
How many flights per day from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI)?
Nonstop flights from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from EYW to STI?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI)?
To avoid possible delays on the Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI) route, aim to fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI) last-minute?
Waiting until just before your departure to book a flight from EYW to STI generally means paying more. Although you may find some last-minute discounts, they're not always guaranteed. Allow some flexibility in your schedule to maximize your chances of getting a bargain.
Is it cheaper to book an EYW to STI flight and hotel package?
You can save money by securing an EYW to STI flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. After choosing your preferred flights and accommodations, you can add extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Key West Intl. Airport (EYW) to Cibao Intl. Airport (STI)?
If you booked your EYW to STI flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you want more information.

Travel information

Origin airport
Key West Intl.
Destination airport
Cibao Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$582
Distance
797 mi

Book with confidence

Key West to Santiago Flights

The cheapest times to fly from Key West to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Key West to Santiago are during the month of November. You can find some of the cheapest flights from Key West to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Key West to Santiago

Sunday is one of the best days to book for cheap flights from Key West to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Key West to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Key West to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $417 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Key West to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Key West to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Key West to Santiago Flights

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*Available to One Key members.