$281 Cheap Flights from Gainesville (GNV) to Santo Domingo (SDQ)

View $281 flight on Wed, Oct 29, 2025Opens in a new window

Popular airlines from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ)

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Cheap Flights from Gainesville to Santo Domingo (GNV-SDQ)

Prices were available within the past 7 days and start at $281 for one-way flights and $472 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, Nov 10 - Tue, Nov 18
GNV
Gainesville
SDQ
Santo Domingo
$472 Roundtrip, found 3 days ago
$472
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Nov 10 from Gainesville to Santo Domingo, returning Tue, Nov 18, priced at $472 found 3 days ago
American Airlines
Mon, Nov 10 - Tue, Nov 18
GNV
Gainesville
SDQ
Santo Domingo
$479 Roundtrip, found 3 days ago
$479
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Nov 10 from Gainesville to Santo Domingo, returning Tue, Nov 18, priced at $479 found 3 days ago
American Airlines
Mon, Nov 10 - Tue, Nov 18
GNV
Gainesville
SDQ
Santo Domingo
$487 Roundtrip, found 3 days ago
$487
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Nov 10 from Gainesville to Santo Domingo, returning Tue, Nov 18, priced at $487 found 3 days ago
American Airlines
Mon, Nov 10 - Tue, Nov 18
GNV
Gainesville
SDQ
Santo Domingo
$496 Roundtrip, found 3 days ago
$496
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Nov 10 from Gainesville to Santo Domingo, returning Tue, Nov 18, priced at $496 found 3 days ago
American Airlines
Mon, Nov 10 - Tue, Nov 18
GNV
Gainesville
SDQ
Santo Domingo
$502 Roundtrip, found 3 days ago
$502
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Nov 10 from Gainesville to Santo Domingo, returning Tue, Nov 18, priced at $502 found 3 days ago
American Airlines
Mon, Nov 10 - Tue, Nov 18
GNV
Gainesville
SDQ
Santo Domingo
$510 Roundtrip, found 3 days ago
$510
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Nov 10 from Gainesville to Santo Domingo, returning Tue, Nov 18, priced at $510 found 3 days ago
Delta
Tue, Sep 30 - Tue, Oct 7
GNV
Gainesville
SDQ
Santo Domingo
$515 Roundtrip, found 4 days ago
$515
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Sep 30 from Gainesville to Santo Domingo, returning Tue, Oct 7, priced at $515 found 4 days ago
American Airlines
Fri, Nov 14 - Sat, Nov 15
GNV
Gainesville
SDQ
Santo Domingo
$517 Roundtrip, found 17 hours ago
$517
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Fri, Nov 14 from Gainesville to Santo Domingo, returning Sat, Nov 15, priced at $517 found 17 hours ago
American Airlines
Sun, Jan 11 - Sat, Jan 17
GNV
Gainesville
SDQ
Santo Domingo
$522 Roundtrip, found 21 hours ago
$522
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Sun, Jan 11 from Gainesville to Santo Domingo, returning Sat, Jan 17, priced at $522 found 21 hours ago
American Airlines
Wed, Oct 8 - Wed, Oct 15
GNV
Gainesville
SDQ
Santo Domingo
$523 Roundtrip, found 3 days ago
$523
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 8 from Gainesville to Santo Domingo, returning Wed, Oct 15, priced at $523 found 3 days ago

Frequently asked questions

How much does a flight from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ) cost?
Snag a cheap one-way flight from $281 or cheap return flight from $472 from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ)?
The cheapest month to fly from GNV to SDQ is November, when there's less demand. Off-peak months are typically when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ)?
To find the cheapest airline that'll fly you from GNV to SDQ, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ)?
You'll need to catch a flight with a layover if you're traveling from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from GNV to SDQ?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ)?
To touch down at Las Americas Intl. Airport (SDQ) on time, pick a flight that leaves Gainesville Regional Airport (GNV) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ) last-minute?
Booking your ticket from GNV to SDQ shortly before your journey is generally more expensive. However, if there's some wiggle room with your itinerary, you could bag a cheap last-minute fare.
Is it cheaper to book a GNV to SDQ flight and hotel package?
Compared with arranging flights and hotels separately, booking a GNV to SDQ flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one place takes the hassle out of travel planning. Simply pick your flights and select from our wide range of hotels, then tailor your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Gainesville Regional Airport (GNV) to Las Americas Intl. Airport (SDQ)?
If you reserved your GNV to SDQ flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

Travel information

Travel information

Origin airport
Gainesville Regional
Destination airport
Las Americas Intl.
Airlines serving
American Airlines, Delta
Roundtrip price
$471
Distance
1110 mi

Book with confidence

Book with confidence

Gainesville to Santo Domingo Flights

The cheapest times to fly from Gainesville to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Gainesville to Santo Domingo are during the month of November. You can find some of the cheapest flights from Gainesville to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Gainesville to Santo Domingo

Sunday is one of the best days to book for cheap flights from Gainesville to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Gainesville to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Gainesville to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $281 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Gainesville to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Gainesville to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Gainesville to Santo Domingo Flights

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*Available to One Key members.