$203 Cheap Flights from Houston (HOU) to Tupelo (TUP)

View $203 flight on Wed, Nov 19, 2025Opens in a new window

Popular airlines from Houston William Hobby Airport (HOU) to Tupelo, MS (TUP-Tupelo Regional)

Cheap Flights from Houston to Tupelo (HOU-TUP)

Prices were available within the past 7 days and start at $203 for one-way flights and $420 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Nov 27 - Fri, Nov 28
HOU
Houston
TUP
Tupelo
$420 Roundtrip, found 4 days ago
$420
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Nov 27 from Houston to Tupelo, returning Fri, Nov 28, priced at $420 found 4 days ago

Alternative airports near Tupelo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tupelo Regional TUP. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $444
TUP
Tupelo Regional
CheapestClosest
Average driving time to city center8 min
Flights from $444

Frequently asked questions

How much does a flight from William P. Hobby Airport (HOU) to Tupelo Regional Airport (TUP) cost?
Snag a cheap one-way flight from $203 or cheap return flight from $420 from William P. Hobby Airport (HOU) to Tupelo Regional Airport (TUP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from William P. Hobby Airport (HOU) to Tupelo Regional Airport (TUP)?
November is the least expensive month to fly from HOU to TUP. Avoiding peak travel times is often the key to landing a great deal.
What is the cheapest airline that flies from William P. Hobby Airport (HOU) to Tupelo Regional Airport (TUP)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from HOU to TUP. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from William P. Hobby Airport (HOU) to Tupelo Regional Airport (TUP)?
There aren't any daily nonstop flights available from William P. Hobby Airport (HOU) to Tupelo Regional Airport (TUP). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from HOU to TUP?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can change depending on a range of factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from William P. Hobby Airport (HOU) to Tupelo Regional Airport (TUP)?
To land at Tupelo Regional Airport (TUP) on schedule, choose a flight that leaves from William P. Hobby Airport (HOU) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from William P. Hobby Airport (HOU) to Tupelo Regional Airport (TUP) last-minute?
Holding off until right before your break to book your flight from HOU to TUP generally means paying more. While you may come across some last-minute discounts, they're not always guaranteed. Keep your travel schedule open to maximize your chances of getting a bargain.
Is it cheaper to book a HOU to TUP flight and hotel package?
You'll typically save money by booking a HOU to TUP flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your ideal flights and accommodations, you can add extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from William P. Hobby Airport (HOU) to Tupelo Regional Airport (TUP)?
Typically, you can reschedule or cancel your HOU to TUP flight. However, there may be additional fees, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like more information, head to our Customer Service portal.

Travel information

Travel information

Origin airport
William P. Hobby
Destination airport
Tupelo Regional
Roundtrip price
$419
Distance
496 mi

Book with confidence

Book with confidence

Houston to Tupelo Flights

The cheapest times to fly from Houston to Tupelo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Houston to Tupelo are during the month of November. You can find some of the cheapest flights from Houston to Tupelo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Houston to Tupelo

Sunday is one of the best days to book for cheap flights from Houston to Tupelo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Houston to Tupelo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Houston to Tupelo in 2025. You can also book with separate airlines for your outbound and return journeys, from $203 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Houston to Tupelo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Houston to Tupelo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Houston to Tupelo Flights

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*Available to One Key members.