$1,313 Cheap Flights from Istanbul (IST) to Chicago (MDW)

View $1,313 flight on Thu, Sep 18, 2025Opens in a new window

Popular airlines from Istanbul Airport (IST) to Chicago Midway Airport (MDW)

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Cheap Flights from Istanbul to Chicago (IST-MDW)

Prices were available within the past 7 days and start at $1,313 for one-way flights and $697 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Feb 4 - Wed, Feb 11
IST
Istanbul
MDW
Chicago
$697 Roundtrip, found 6 days ago
$697
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Feb 4 from Istanbul to Chicago, returning Wed, Feb 11, priced at $697 found 6 days ago
Delta
Mon, Nov 10 - Sat, Nov 22
IST
Istanbul
MDW
Chicago
$698 Roundtrip, found 5 days ago
$698
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Nov 10 from Istanbul to Chicago, returning Sat, Nov 22, priced at $698 found 5 days ago
Delta
Sat, Sep 20 - Sat, Jan 17
IST
Istanbul
MDW
Chicago
$716 Roundtrip, found 1 day ago
$716
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Sep 20 from Istanbul to Chicago, returning Sat, Jan 17, priced at $716 found 1 day ago
Delta
Sat, Nov 22 - Sat, Nov 29
IST
Istanbul
MDW
Chicago
$723 Roundtrip, found 6 days ago
$723
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Nov 22 from Istanbul to Chicago, returning Sat, Nov 29, priced at $723 found 6 days ago
Air France
Mon, Nov 10 - Sat, Nov 22
IST
Istanbul
MDW
Chicago
$724 Roundtrip, found 5 days ago
$724
Roundtrip
found 5 days ago
Select Air France flight, departing Mon, Nov 10 from Istanbul to Chicago, returning Sat, Nov 22, priced at $724 found 5 days ago
Delta
Thu, Dec 25 - Tue, Jan 6
IST
Istanbul
MDW
Chicago
$729 Roundtrip, found 6 days ago
$729
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Dec 25 from Istanbul to Chicago, returning Tue, Jan 6, priced at $729 found 6 days ago
KLM
Sat, Sep 20 - Thu, Nov 20
IST
Istanbul
MDW
Chicago
$741 Roundtrip, found 2 days ago
$741
Roundtrip
found 2 days ago
Select KLM flight, departing Sat, Sep 20 from Istanbul to Chicago, returning Thu, Nov 20, priced at $741 found 2 days ago
Air France
Mon, Oct 20 - Fri, Oct 31
IST
Istanbul
MDW
Chicago
$746 Roundtrip, found 3 days ago
$746
Roundtrip
found 3 days ago
Select Air France flight, departing Mon, Oct 20 from Istanbul to Chicago, returning Fri, Oct 31, priced at $746 found 3 days ago
KLM
Tue, Oct 21 - Sat, Nov 1
IST
Istanbul
MDW
Chicago
$748 Roundtrip, found 5 days ago
$748
Roundtrip
found 5 days ago
Select KLM flight, departing Tue, Oct 21 from Istanbul to Chicago, returning Sat, Nov 1, priced at $748 found 5 days ago
Delta
Sat, Nov 22 - Sat, Nov 29
IST
Istanbul
MDW
Chicago
$750 Roundtrip, found 20 hours ago
$750
Roundtrip
found 20 hours ago
Select Delta flight, departing Sat, Nov 22 from Istanbul to Chicago, returning Sat, Nov 29, priced at $750 found 20 hours ago
Delta
Thu, Dec 25 - Tue, Jan 6
IST
Istanbul
MDW
Chicago
$755 Roundtrip, found 6 days ago
$755
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Dec 25 from Istanbul to Chicago, returning Tue, Jan 6, priced at $755 found 6 days ago

Alternative airports near Chicago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to O'Hare Intl. ORD. Cheapest option available. Average driving time to city center is 23 minutes. Flights from $607
ORD
O'Hare Intl.
Cheapest
Average driving time to city center23 min
Flights from $607
Flights from Istanbul (IST) to Chicago (MDW)
Origin airport
Istanbul
Destination airport
Midway Intl.
Airlines serving
Delta
Roundtrip price
$696
Distance
5463 mi

Istanbul to Chicago Flights

The cheapest times to fly from Istanbul to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Istanbul to Chicago are during the month of February. You can find some of the cheapest flights from Istanbul to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Istanbul to Chicago

Sunday is one of the best days to book for cheap flights from Istanbul to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Istanbul to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Istanbul to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $1,313 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Istanbul to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Istanbul to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Istanbul (IST) to Midway Intl. Airport (MDW) cost?
Snag a cheap one-way flight from $1,313 or cheap return flight from $697 from Istanbul (IST) to Midway Intl. Airport (MDW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Istanbul (IST) to Midway Intl. Airport (MDW)?
Planning your getaway for February is a good way to save, as it's the cheapest month for flights between IST and MDW. You'll usually find the lowest prices during off-peak months.
What is the cheapest airline that flies from Istanbul (IST) to Midway Intl. Airport (MDW)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll fly you from IST to MDW. Then, sort your results by "Price (lowest to highest)" to snap up a good deal.
How many flights per day from Istanbul (IST) to Midway Intl. Airport (MDW)?
You'll have to hop on a flight with a layover when traveling from Istanbul (IST) to Midway Intl. Airport (MDW). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from IST to MDW?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change depending on a number of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Istanbul (IST) to Midway Intl. Airport (MDW)?
Select a flight from Istanbul (IST) to Midway Intl. Airport (MDW) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Istanbul (IST) to Midway Intl. Airport (MDW) last-minute?
Holding off until just before your departure to book a ticket from IST to MDW generally means paying more. While you may come across some last-minute offers, they're not always guaranteed. Keep your travel schedule open to maximize your chances of snagging a bargain.
Is it cheaper to book an IST to MDW flight and hotel package?
Compared with arranging flights and hotels separately, booking an IST to MDW flight and hotel package with Expedia could result in significant savings. Better yet, managing everything in one place takes the hassle out of planning your trip. Just pick your flights and choose from our extensive range of stays, then personalize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Istanbul (IST) to Midway Intl. Airport (MDW)?
It's usually possible to cancel or reschedule your IST to MDW flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.