$458 Cheap Flights from Lisbon (LIS) to Panama City (PTY)

You can find cheap one-way flights from $458 and cheap return flights $714 Lisbon (LIS-Humberto Delgado) to Panama City (PTY-Tocumen Intl.) with Expedia. One-way flights usually range from $777 to $3058, and return flights typically cost between $1192 and $5431. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Lisbon (LIS-Humberto Delgado) to Panama City (PTY-Tocumen Intl.) ticket fares go up or down.

*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.

The cheapest month to fly from LIS to PTY is October when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.

Enter LIS to PTY and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

United is one of the cheapest airlines offering connecting flights from Lisbon (LIS) to Panama City (PTY) with return tickets starting from around $987 with a layover in Washington Dulles Intl. (IAD). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.

*Prices based on flights available on Expedia in the last year.

To find a cheap flight from Lisbon (LIS-Humberto Delgado) to Panama City (PTY-Tocumen Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.

The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.

The earliest flight from Lisbon (LIS) to Panama City (PTY) usually leaves at around 5:00 AM, with KLM and Air France operating this route. An early departure can help you make the most of your time in Panama City. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.

The most popular departure times for flights from Lisbon (LIS) to Panama City (PTY) are from 9am to 12pm. About 46% of passengers prefer this time window. Many major carriers, including United Airlines, Air Europa, and Copa Airlines, offer flights during this window. This timing is great for those looking to travel during the day.

Flying from LIS to PTY with a connection usually takes about 17 hours, traveling roughly 4,766 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

Business class is available on flights from LIS to PTY. Airlines that offer business class service on this route include:

• Air Europa
• Turkish Airlines
• Swiss International Air Lines
• United Airlines
• Iberia
• Lufthansa
• British Airways
• TAP Portugal
• Air Canada
• Brussels Airlines

It's easy to earn miles on a Lisbon (LIS-Humberto Delgado) to Panama City (PTY-Tocumen Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

From Humberto Delgado (LIS), you can fly into Tocumen Intl. (PTY) and Northwest Florida Beaches Intl. (ECP) in Panama City. Some flights may connect through major hubs like Adolfo Suarez Madrid-Barajas (MAD), Frankfurt Intl. (FRA), Washington Dulles Intl. (IAD) before reaching Panama City. Compare routes and airports on Expedia to find the best flight options for your travel plans.

Typically, booking a last minute flight from Lisbon (LIS-Humberto Delgado) to Panama City (PTY-Tocumen Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

Securing a Lisbon (LIS-Humberto Delgado) to Panama City (PTY-Tocumen Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

If you booked your Lisbon (LIS-Humberto Delgado) to Panama City (PTY-Tocumen Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.