$693 Cheap Flights from La Serena (LSC) to Mexico City (MEX)

View $693 flight on Thu, Dec 18, 2025Opens in a new window

Popular airlines from La Serena (LSC-La Florida) to Benito Juarez International Airport (MEX)

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Cheap Flights from La Serena to Mexico City (LSC-MEX)

Prices were available within the past 7 days and start at $693 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX) cost?
Get a cheap one-way flight from $693 or cheap return flight from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX)?
is the cheapest month to fly from LSC to MEX. Traveling outside of peak seasons is often the key to better flight prices.
What is the cheapest airline that flies from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest LSC to MEX flight.
How many flights per day from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX)?
There are no daily direct flights available from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from LSC to MEX?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX)?
Book a flight from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX) that leaves before 3 PM to reduce the likelihood of delays. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX) last-minute?
Last-minute bookings from LSC to MEX are typically more expensive. To secure the cheapest rates, start searching for flights as soon as possible. That said, if your travel plans are flexible, it's possible to score a cheap fare right before your trip.
Is it cheaper to book a LSC to MEX flight and hotel package?
You can save money by booking a LSC to MEX flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. Once you've selected your ideal accommodations and flights, you can add extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from La Florida Airport (LSC) to Mexico City Intl. Airport (MEX)?
Typically, it's possible to cancel or reschedule your LSC to MEX flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
La Florida
Destination airport
Mexico City Intl.
Distance
3881 mi

Book with confidence

La Serena to Mexico City Flights

The cheapest times to fly from La Serena to Mexico City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from La Serena to Mexico City are during the month of . You can find some of the cheapest flights from La Serena to Mexico City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from La Serena to Mexico City

Sunday is one of the best days to book for cheap flights from La Serena to Mexico City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from La Serena to Mexico City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from La Serena to Mexico City in 2025. You can also book with separate airlines for your outbound and return journeys, from $693 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap La Serena to Mexico City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your La Serena to Mexico City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

La Serena to Mexico City Flights

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*Available to One Key members.