Cheap Flights from La Crosse (LSE) to Santa Fe (SAF)

Popular airlines from La Crosse, WI (LSE-La Crosse Municipal) to Santa Fe Municipal Airport (SAF)

Cheap Flights from La Crosse to Santa Fe (LSE-SAF)

Prices were available within the past 7 days and start at for one-way flights and $621 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Sep 30 - Sat, Oct 4
LSE
La Crosse
SAF
Santa Fe
$621 Roundtrip, found 3 days ago
$621
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Sep 30 from La Crosse to Santa Fe, returning Sat, Oct 4, priced at $621 found 3 days ago
American Airlines
Tue, Sep 30 - Fri, Oct 3
LSE
La Crosse
SAF
Santa Fe
$661 Roundtrip, found 3 days ago
$661
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Sep 30 from La Crosse to Santa Fe, returning Fri, Oct 3, priced at $661 found 3 days ago
American Airlines
Sat, Oct 4 - Mon, Oct 6
LSE
La Crosse
SAF
Santa Fe
$724 Roundtrip, found 3 days ago
$724
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Oct 4 from La Crosse to Santa Fe, returning Mon, Oct 6, priced at $724 found 3 days ago
American Airlines
Mon, Sep 29 - Mon, Oct 6
LSE
La Crosse
SAF
Santa Fe
$734 Roundtrip, found 3 days ago
$734
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Sep 29 from La Crosse to Santa Fe, returning Mon, Oct 6, priced at $734 found 3 days ago
American Airlines
Sat, Oct 4 - Wed, Oct 8
LSE
La Crosse
SAF
Santa Fe
$744 Roundtrip, found 3 days ago
$744
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Oct 4 from La Crosse to Santa Fe, returning Wed, Oct 8, priced at $744 found 3 days ago
American Airlines
Mon, Sep 29 - Sat, Oct 4
LSE
La Crosse
SAF
Santa Fe
$754 Roundtrip, found 3 days ago
$754
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Sep 29 from La Crosse to Santa Fe, returning Sat, Oct 4, priced at $754 found 3 days ago
American Airlines
Fri, Oct 3 - Sat, Oct 4
LSE
La Crosse
SAF
Santa Fe
$781 Roundtrip, found 3 days ago
$781
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Oct 3 from La Crosse to Santa Fe, returning Sat, Oct 4, priced at $781 found 3 days ago
American Airlines
Wed, Oct 1 - Mon, Oct 6
LSE
La Crosse
SAF
Santa Fe
$833 Roundtrip, found 3 days ago
$833
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 1 from La Crosse to Santa Fe, returning Mon, Oct 6, priced at $833 found 3 days ago
American Airlines
Wed, Oct 1 - Sat, Oct 4
LSE
La Crosse
SAF
Santa Fe
$851 Roundtrip, found 3 days ago
$851
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 1 from La Crosse to Santa Fe, returning Sat, Oct 4, priced at $851 found 3 days ago
American Airlines
Wed, Oct 1 - Wed, Oct 8
LSE
La Crosse
SAF
Santa Fe
$853 Roundtrip, found 3 days ago
$853
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 1 from La Crosse to Santa Fe, returning Wed, Oct 8, priced at $853 found 3 days ago
American Airlines
Thu, Oct 2 - Mon, Oct 6
LSE
La Crosse
SAF
Santa Fe
$864 Roundtrip, found 3 days ago
$864
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 2 from La Crosse to Santa Fe, returning Mon, Oct 6, priced at $864 found 3 days ago
American Airlines
Wed, Oct 1 - Fri, Oct 3
LSE
La Crosse
SAF
Santa Fe
$891 Roundtrip, found 3 days ago
$891
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 1 from La Crosse to Santa Fe, returning Fri, Oct 3, priced at $891 found 3 days ago
American Airlines
Thu, Oct 2 - Sat, Oct 4
LSE
La Crosse
SAF
Santa Fe
$911 Roundtrip, found 3 days ago
$911
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 2 from La Crosse to Santa Fe, returning Sat, Oct 4, priced at $911 found 3 days ago
American Airlines
Tue, Sep 30 - Sun, Oct 5
LSE
La Crosse
SAF
Santa Fe
$931 Roundtrip, found 3 days ago
$931
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Sep 30 from La Crosse to Santa Fe, returning Sun, Oct 5, priced at $931 found 3 days ago
American Airlines
Thu, Oct 2 - Fri, Oct 3
LSE
La Crosse
SAF
Santa Fe
$951 Roundtrip, found 3 days ago
$951
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 2 from La Crosse to Santa Fe, returning Fri, Oct 3, priced at $951 found 3 days ago
American Airlines
Thu, Oct 2 - Sun, Oct 5
LSE
La Crosse
SAF
Santa Fe
$981 Roundtrip, found 3 days ago
$981
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 2 from La Crosse to Santa Fe, returning Sun, Oct 5, priced at $981 found 3 days ago
American Airlines
Thu, Oct 2 - Sun, Oct 5
LSE
La Crosse
SAF
Santa Fe
$1,051 Roundtrip, found 3 days ago
$1,051
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 2 from La Crosse to Santa Fe, returning Sun, Oct 5, priced at $1,051 found 3 days ago
American Airlines
Thu, Oct 2 - Sun, Oct 5
LSE
La Crosse
SAF
Santa Fe
$1,059 Roundtrip, found 3 days ago
$1,059
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 2 from La Crosse to Santa Fe, returning Sun, Oct 5, priced at $1,059 found 3 days ago
American Airlines
Thu, Oct 2 - Sun, Oct 5
LSE
La Crosse
SAF
Santa Fe
$1,081 Roundtrip, found 3 days ago
$1,081
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 2 from La Crosse to Santa Fe, returning Sun, Oct 5, priced at $1,081 found 3 days ago
American Airlines
Thu, Oct 2 - Sun, Oct 5
LSE
La Crosse
SAF
Santa Fe
$1,085 Roundtrip, found 3 days ago
$1,085
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 2 from La Crosse to Santa Fe, returning Sun, Oct 5, priced at $1,085 found 3 days ago
Flights from La Crosse (LSE) to Santa Fe (SAF)
Origin airport
La Crosse Municipal
Destination airport
Santa Fe Municipal
Roundtrip price
$620
Distance
969 mi

La Crosse to Santa Fe Flights

The cheapest times to fly from La Crosse to Santa Fe

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from La Crosse to Santa Fe are during the month of September. You can find some of the cheapest flights from La Crosse to Santa Fe with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from La Crosse to Santa Fe

Sunday is one of the best days to book for cheap flights from La Crosse to Santa Fe: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from La Crosse to Santa Fe

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from La Crosse to Santa Fe in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap La Crosse to Santa Fe flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your La Crosse to Santa Fe airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF) cost?
Grab a cheap one-way flight or cheap return flight from $621 from La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF)?
Traveling in September may help you find better deals, as it's the cheapest month for flights between LSE and SAF. You'll usually find the lowest fares during off-peak months.
What is the cheapest airline that flies from La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest LSE to SAF flight.
How many flights per day from La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF)?
There aren't any daily direct flights departing from La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from LSE to SAF?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF)?
To avoid possible delays on the La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF) route, travel before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF) last-minute?
Last-minute fares from LSE to SAF are generally more expensive. To lock in the lowest rates, start searching for flights well ahead of time. That being said, if you're flexible with your travel plans, it's possible to find a cheap ticket just before your departure.
Is it cheaper to book a LSE to SAF flight and hotel package?
You'll typically save money by securing a LSE to SAF flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After selecting your ideal accommodations and flights, consider other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from La Crosse Municipal Airport (LSE) to Santa Fe Municipal Airport (SAF)?
If you reserved your LSE to SAF flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

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*Available to One Key members.