$191 Cheap Flights from Medellín (MDE) to Columbus (CMH)

View $191 flight on Thu, Nov 6, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH)

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Cheap Flights from Medellín to Columbus (MDE-CMH)

Prices were available within the past 7 days and start at $191 for one-way flights and $332 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Thu, Oct 23 - Mon, Oct 27
MDE
Medellin
CMH
Columbus
$332 Roundtrip, found 6 days ago
$332
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Thu, Oct 23 from Medellin to Columbus, returning Mon, Oct 27, priced at $332 found 6 days ago
Spirit Airlines
Wed, Dec 3 - Wed, Dec 10
MDE
Medellin
CMH
Columbus
$397 Roundtrip, found 2 days ago
$397
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Wed, Dec 3 from Medellin to Columbus, returning Wed, Dec 10, priced at $397 found 2 days ago
Spirit Airlines
Fri, Jan 23 - Fri, Jan 30
MDE
Medellin
CMH
Columbus
$409 Roundtrip, found 6 days ago
$409
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Fri, Jan 23 from Medellin to Columbus, returning Fri, Jan 30, priced at $409 found 6 days ago
Spirit Airlines
Mon, Nov 24 - Tue, Dec 2
MDE
Medellin
CMH
Columbus
$419 Roundtrip, found 2 days ago
$419
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Mon, Nov 24 from Medellin to Columbus, returning Tue, Dec 2, priced at $419 found 2 days ago
Spirit Airlines
Wed, Dec 3 - Wed, Dec 10
MDE
Medellin
CMH
Columbus
$430 Roundtrip, found 2 days ago
$430
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Wed, Dec 3 from Medellin to Columbus, returning Wed, Dec 10, priced at $430 found 2 days ago
Spirit Airlines
Fri, Jan 23 - Fri, Jan 30
MDE
Medellin
CMH
Columbus
$445 Roundtrip, found 6 days ago
$445
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Fri, Jan 23 from Medellin to Columbus, returning Fri, Jan 30, priced at $445 found 6 days ago
Copa
Mon, Nov 24 - Tue, Dec 2
MDE
Medellin
CMH
Columbus
$506 Roundtrip, found 2 days ago
$506
Roundtrip
found 2 days ago
Select Copa flight, departing Mon, Nov 24 from Medellin to Columbus, returning Tue, Dec 2, priced at $506 found 2 days ago
United
Wed, Dec 17 - Wed, Dec 31
MDE
Medellin
CMH
Columbus
$612 Roundtrip, found 3 hours ago
$612
Roundtrip
found 3 hours ago
Select United flight, departing Wed, Dec 17 from Medellin to Columbus, returning Wed, Dec 31, priced at $612 found 3 hours ago
American Airlines
Tue, Dec 9 - Mon, Dec 29
MDE
Medellin
CMH
Columbus
$612 Roundtrip, found 2 days ago
$612
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Dec 9 from Medellin to Columbus, returning Mon, Dec 29, priced at $612 found 2 days ago
Delta
Tue, Mar 3 - Mon, Mar 16
MDE
Medellin
CMH
Columbus
$624 Roundtrip, found 1 day ago
$624
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Mar 3 from Medellin to Columbus, returning Mon, Mar 16, priced at $624 found 1 day ago

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH) cost?
Get a cheap one-way flight from $191 or cheap return flight from $332 from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH)?
Flying in October is a great way to save, as it's the cheapest month for flights between MDE and CMH. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH)?
To find the cheapest airline flying from MDE to CMH, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH)?
Nonstop flights from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MDE to CMH?
Usually you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH)?
To arrive at John Glenn Columbus Intl. Airport (CMH) on time, book a flight that leaves from Jose Maria Cordova Intl. Airport (MDE) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH) last-minute?
Waiting until just before your departure to book a flight from MDE to CMH generally means paying more. While it's possible to find some last-minute deals, they're not always guaranteed. Keep your travel plans flexible to maximize your chances of scoring a bargain.
Is it cheaper to book a MDE to CMH flight and hotel package?
You'll generally save money by booking a MDE to CMH flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've selected your preferred flights and accommodations, consider other add-ons like activities, car rentals and tours.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to John Glenn Columbus Intl. Airport (CMH)?
In most instances, you can cancel or reschedule your MDE to CMH flight. However, there may be additional fees, especially if you booked over 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you'd like further details, visit our Customer Service portal.

Travel information

Origin airport
José María Córdova Intl.
Destination airport
John Glenn Columbus Intl.
Airlines serving
American Airlines, Copa, Delta, LATAM Airlines Group, Spirit Airlines, United, avianca
Roundtrip price
$331
Distance
2382 mi

Book with confidence

Medellín to Columbus Flights

The cheapest times to fly from Medellín to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Columbus are during the month of October. You can find some of the cheapest flights from Medellín to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Columbus

Sunday is one of the best days to book for cheap flights from Medellín to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Columbus in 2025. You can also book with separate airlines for your outbound and return journeys, from $191 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medellín to Columbus Flights

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*Available to One Key members.