$339 Cheap Flights from Medellín (MDE) to Denver (DEN)

View $339 flight on Sun, Dec 14, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN)

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Cheap Flights from Medellín to Denver (MDE-DEN)

Prices were available within the past 7 days and start at $339 for one-way flights and $563 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Tue, Feb 10 - Tue, Feb 24
MDE
Medellin
DEN
Denver
$563 Roundtrip, found 1 day ago
$563
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Feb 10 from Medellin to Denver, returning Tue, Feb 24, priced at $563 found 1 day ago
Copa
Fri, Nov 7 - Mon, Nov 10
MDE
Medellin
DEN
Denver
$565 Roundtrip, found 22 hours ago
$565
Roundtrip
found 22 hours ago
Select Copa flight, departing Fri, Nov 7 from Medellin to Denver, returning Mon, Nov 10, priced at $565 found 22 hours ago
American Airlines
Thu, Nov 6 - Mon, Nov 10
MDE
Medellin
DEN
Denver
$577 Roundtrip, found 11 hours ago
$577
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Thu, Nov 6 from Medellin to Denver, returning Mon, Nov 10, priced at $577 found 11 hours ago
United
Thu, Nov 6 - Mon, Nov 10
MDE
Medellin
DEN
Denver
$577 Roundtrip, found 11 hours ago
$577
Roundtrip
found 11 hours ago
Select United flight, departing Thu, Nov 6 from Medellin to Denver, returning Mon, Nov 10, priced at $577 found 11 hours ago
Copa
Tue, Feb 10 - Tue, Feb 24
MDE
Medellin
DEN
Denver
$579 Roundtrip, found 1 day ago
$579
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Feb 10 from Medellin to Denver, returning Tue, Feb 24, priced at $579 found 1 day ago
Copa
Fri, Nov 7 - Mon, Nov 10
MDE
Medellin
DEN
Denver
$581 Roundtrip, found 22 hours ago
$581
Roundtrip
found 22 hours ago
Select Copa flight, departing Fri, Nov 7 from Medellin to Denver, returning Mon, Nov 10, priced at $581 found 22 hours ago
United
Thu, Nov 20 - Sun, Nov 30
MDE
Medellin
DEN
Denver
$586 Roundtrip, found 12 hours ago
$586
Roundtrip
found 12 hours ago
Select United flight, departing Thu, Nov 20 from Medellin to Denver, returning Sun, Nov 30, priced at $586 found 12 hours ago
JetBlue Airways
Fri, Feb 6 - Tue, Mar 24
MDE
Medellin
DEN
Denver
$590 Roundtrip, found 2 days ago
$590
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Fri, Feb 6 from Medellin to Denver, returning Tue, Mar 24, priced at $590 found 2 days ago
Copa
Sun, Feb 1 - Wed, Feb 4
MDE
Medellin
DEN
Denver
$595 Roundtrip, found 1 day ago
$595
Roundtrip
found 1 day ago
Select Copa flight, departing Sun, Feb 1 from Medellin to Denver, returning Wed, Feb 4, priced at $595 found 1 day ago
Aeromexico
Tue, Feb 10 - Tue, Feb 24
MDE
Medellin
DEN
Denver
$643 Roundtrip, found 1 day ago
$643
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Tue, Feb 10 from Medellin to Denver, returning Tue, Feb 24, priced at $643 found 1 day ago

Find the cheapest month to fly from Medellín (MDE) to Denver (DEN)

March is typically the cheapest month to fly

From $475 - $973 per traveler.

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN) cost?
Snag a cheap one-way flight from $339 or cheap return flight from $563 from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN)?
February is the most affordable month to fly from MDE to DEN. Traveling outside of peak seasons is often the key to finding better deals on flights.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN)?
To find the cheapest airline that'll fly you from MDE to DEN, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN)?
You'll have to catch a flight with a layover when traveling from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from MDE to DEN?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN)?
Select a flight from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN) that leaves before 3 PM to reduce the likelihood of delays. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN) last-minute?
Booking your ticket from MDE to DEN shortly before your trip is usually more expensive. However, if there's some wiggle room with your travel dates and times, you could grab a cheap last-minute fare.
Is it cheaper to book a MDE to DEN flight and hotel package?
You can save money by securing a MDE to DEN flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. After choosing your ideal flights and accommodations, you can add extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Denver Intl. Airport (DEN)?
If you booked your MDE to DEN flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the fare type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

Travel information

Origin airport
José María Córdova Intl.
Destination airport
Denver Intl.
Airlines serving
Aeromexico, Air Canada, American Airlines, Copa, Delta, JetBlue Airways, LATAM Airlines Group, United, avianca
Roundtrip price
$562
Distance
2950 mi

Book with confidence

Medellín to Denver Flights

The cheapest times to fly from Medellín to Denver

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Denver are during the month of February. You can find some of the cheapest flights from Medellín to Denver with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Denver

Sunday is one of the best days to book for cheap flights from Medellín to Denver: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Denver

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Denver in 2025. You can also book with separate airlines for your outbound and return journeys, from $339 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Denver flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Denver airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medellín to Denver Flights

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*Available to One Key members.