$136 Cheap Flights from Moline (MLI) to Charleston (CHS)

View $136 flight on Tue, Sep 2, 2025Opens in a new window

Popular airlines from Quad City Intl. Airport (MLI) to Charleston Intl. Airport (CHS)

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Cheap Flights from Moline to Charleston (MLI-CHS)

Prices were available within the past 7 days and start at $136 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Sep 2 - Tue, Sep 9
MLI
Moline
CHS
Charleston
$249 Roundtrip, found 6 hours ago
$249
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Sep 2 from Moline to Charleston, returning Tue, Sep 9, priced at $249 found 6 hours ago
Delta
Tue, Sep 2 - Tue, Sep 9
MLI
Moline
CHS
Charleston
$249 Roundtrip, found 6 hours ago
$249
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Sep 2 from Moline to Charleston, returning Tue, Sep 9, priced at $249 found 6 hours ago
United
Sat, May 2 - Sat, May 9
MLI
Moline
CHS
Charleston
$252 Roundtrip, found 2 days ago
$252
Roundtrip
found 2 days ago
Select United flight, departing Sat, May 2 from Moline to Charleston, returning Sat, May 9, priced at $252 found 2 days ago
Delta
Sat, Jul 19 - Fri, Jul 25
MLI
Moline
CHS
Charleston
$254 Roundtrip, just found
$254
Roundtrip
just found
Select Delta flight, departing Sat, Jul 19 from Moline to Charleston, returning Fri, Jul 25, priced at $254 just found
American Airlines
Wed, Aug 27 - Sun, Aug 31
MLI
Moline
CHS
Charleston
$254 Roundtrip, found 2 days ago
$254
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Aug 27 from Moline to Charleston, returning Sun, Aug 31, priced at $254 found 2 days ago
United
Sat, May 2 - Sat, May 9
MLI
Moline
CHS
Charleston
$257 Roundtrip, found 2 days ago
$257
Roundtrip
found 2 days ago
Select United flight, departing Sat, May 2 from Moline to Charleston, returning Sat, May 9, priced at $257 found 2 days ago
American Airlines
Sat, Jul 19 - Thu, Jul 24
MLI
Moline
CHS
Charleston
$259 Roundtrip, just found
$259
Roundtrip
just found
Select American Airlines flight, departing Sat, Jul 19 from Moline to Charleston, returning Thu, Jul 24, priced at $259 just found
Delta
Tue, Sep 2 - Tue, Sep 9
MLI
Moline
CHS
Charleston
$260 Roundtrip, found 6 hours ago
$260
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Sep 2 from Moline to Charleston, returning Tue, Sep 9, priced at $260 found 6 hours ago
Delta
Fri, Jul 11 - Wed, Jul 30
MLI
Moline
CHS
Charleston
$265 Roundtrip, found 6 days ago
$265
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Jul 11 from Moline to Charleston, returning Wed, Jul 30, priced at $265 found 6 days ago
American Airlines
Wed, Aug 27 - Sun, Aug 31
MLI
Moline
CHS
Charleston
$265 Roundtrip, found 2 days ago
$265
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Aug 27 from Moline to Charleston, returning Sun, Aug 31, priced at $265 found 2 days ago

Find the cheapest month to fly from Moline (MLI) to Charleston (CHS)

February is typically the cheapest month to fly

From $198 - $443 per traveler.

Graph displaying average flight prices per month

Flights from Moline (MLI) to Charleston (CHS)
Origin airport
Quad City Intl.
Destination airport
Charleston Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
825 mi

Moline to Charleston Flights

The cheapest times to fly from Moline to Charleston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Moline to Charleston are during the month of September. You can find some of the cheapest flights from Moline to Charleston with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Moline to Charleston

Sunday is one of the best days to book for cheap flights from Moline to Charleston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Moline to Charleston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Moline to Charleston in 2025. You can also book with separate airlines for your outbound and return journeys, from $136 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Moline to Charleston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Moline to Charleston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Quad City Intl. Airport (MLI) to Charleston Intl. Airport (CHS) cost?
Discover the latest flight deals from MLI to CHS by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MLI to CHS?
The cheapest flights from MLI to CHS are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from MLI to CHS?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from MLI to CHS. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Quad City Intl. Airport (MLI) to Charleston Intl. Airport (CHS)?
Direct flights from Quad City Intl. Airport (MLI) to Charleston Intl. Airport (CHS) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MLI to CHS?
Usually you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can change depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Quad City Intl. Airport (MLI) to Charleston Intl. Airport (CHS)?
Select a flight from Quad City Intl. Airport (MLI) to Charleston Intl. Airport (CHS) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Quad City Intl. Airport (MLI) to Charleston Intl. Airport (CHS) last-minute?
Booking your ticket from MLI to CHS just before your trip is usually more expensive. However, if there's some wiggle room with your travel times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a MLI to CHS flight and hotel package?
Opting for a MLI to CHS flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Select from our impressive range of accommodations and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Quad City Intl. Airport (MLI) to Charleston Intl. Airport (CHS)?
If you booked your MLI to CHS flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more details.

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*Available to One Key members.