$166 Cheap Flights from Pereira (PEI) to Panama City (PTY)

View $166 flight on Mon, Dec 15, 2025Opens in a new window

Popular airlines from Pereira (PEI-Matecaña Intl.) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Pereira to Panama City (PEI-PTY)

Prices were available within the past 7 days and start at $166 for one-way flights and $285 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, Nov 26 - Sat, Dec 6
PEI
Pereira
PTY
Panama City
$285 Roundtrip, found 8 hours ago
$285
Roundtrip
found 8 hours ago
Select Copa flight, departing Wed, Nov 26 from Pereira to Panama City, returning Sat, Dec 6, priced at $285 found 8 hours ago
Copa
Wed, Nov 26 - Sat, Dec 6
PEI
Pereira
PTY
Panama City
$296 Roundtrip, found 8 hours ago
$296
Roundtrip
found 8 hours ago
Select Copa flight, departing Wed, Nov 26 from Pereira to Panama City, returning Sat, Dec 6, priced at $296 found 8 hours ago
Copa
Thu, Nov 6 - Fri, Nov 7
PEI
Pereira
PTY
Panama City
$338 Roundtrip, found 2 days ago
$338
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Nov 6 from Pereira to Panama City, returning Fri, Nov 7, priced at $338 found 2 days ago
avianca
Sat, Nov 8 - Mon, Nov 10
PEI
Pereira
PTY
Panama City
$338 Roundtrip, found 2 days ago
$338
Roundtrip
found 2 days ago
Select avianca flight, departing Sat, Nov 8 from Pereira to Panama City, returning Mon, Nov 10, priced at $338 found 2 days ago
Copa
Sat, Nov 15 - Thu, Jan 15
PEI
Pereira
PTY
Panama City
$340 Roundtrip, found 5 days ago
$340
Roundtrip
found 5 days ago
Select Copa flight, departing Sat, Nov 15 from Pereira to Panama City, returning Thu, Jan 15, priced at $340 found 5 days ago
avianca
Tue, Feb 10 - Sat, Feb 14
PEI
Pereira
PTY
Panama City
$342 Roundtrip, found 3 days ago
$342
Roundtrip
found 3 days ago
Select avianca flight, departing Tue, Feb 10 from Pereira to Panama City, returning Sat, Feb 14, priced at $342 found 3 days ago
avianca
Wed, Nov 26 - Sat, Dec 6
PEI
Pereira
PTY
Panama City
$346 Roundtrip, found 8 hours ago
$346
Roundtrip
found 8 hours ago
Select avianca flight, departing Wed, Nov 26 from Pereira to Panama City, returning Sat, Dec 6, priced at $346 found 8 hours ago
avianca
Sat, Dec 20 - Tue, Jan 13
PEI
Pereira
PTY
Panama City
$349 Roundtrip, found 2 hours ago
$349
Roundtrip
found 2 hours ago
Select avianca flight, departing Sat, Dec 20 from Pereira to Panama City, returning Tue, Jan 13, priced at $349 found 2 hours ago
avianca
Wed, Nov 19 - Sun, Nov 23
PEI
Pereira
PTY
Panama City
$353 Roundtrip, found 3 days ago
$353
Roundtrip
found 3 days ago
Select avianca flight, departing Wed, Nov 19 from Pereira to Panama City, returning Sun, Nov 23, priced at $353 found 3 days ago
avianca
Tue, Feb 10 - Sat, Feb 14
PEI
Pereira
PTY
Panama City
$354 Roundtrip, found 3 days ago
$354
Roundtrip
found 3 days ago
Select avianca flight, departing Tue, Feb 10 from Pereira to Panama City, returning Sat, Feb 14, priced at $354 found 3 days ago

Find the cheapest month to fly from Pereira (PEI) to Panama City (PTY)

November is typically the cheapest month to fly

From $235 - $416 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $338
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $338
Flights from Pereira (PEI) to Panama City (PTY)
Origin airport
Matecaña Intl.
Destination airport
Tocumen Intl.
Airlines serving
Copa, avianca
Roundtrip price
$285
Distance
385 mi
Average flight time
1 hour 28 mins

Pereira to Panama City Flights

The cheapest times to fly from Pereira to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pereira to Panama City are during the month of November. You can find some of the cheapest flights from Pereira to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pereira to Panama City

Sunday is one of the best days to book for cheap flights from Pereira to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pereira to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pereira to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $166 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pereira to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pereira to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY) cost?
Lock in a cheap one-way flight from $166 or cheap return flight from $285 from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY)?
The cheapest month to fly from PEI to PTY is November, when there's less demand. Off-peak season is often when airlines offer better prices between these airports.
Which airlines fly direct from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY)?
If you're departing from Matecana Intl. Airport (PEI), you can hop on a nonstop flight to Tocumen Intl. Airport (PTY) with Copa Airlines.
What is the cheapest airline that flies from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest PEI to PTY flight.
How many flights per day from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY)?
On average, there is just 1 nonstop flight leaving from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY) per day. If this doesn't fit your travel plans, check out flights with a layover. Simply filter your search on Expedia to include one or more stops to discover the next best option.
What are the most popular departure times for flights from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY)?
Flights between PEI and PTY are their busiest at 5 AM. If you'd like a more relaxed trip and potentially cheaper tickets, choose a time when demand is lower.
What day of the week has the most flights from PEI to PTY?
Wednesday offers the most flights from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY). Consider taking off on this day and you'll have the best chance of finding a schedule that works for you.
What is the earliest flight from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY)?
Matecana Intl. Airport (PEI)'s first flight to Tocumen Intl. Airport (PTY) takes off at approximately 5:11AM UTC-5. With a total travel time of 1h 27m, you'll arrive at around 6:38AM UTC-5.
How long does it take to fly from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY)?
It takes roughly 1 hour and 28 minutes to travel the 390 mi from PEI to PTY.
What airline has the least delays from PEI to PTY?
Copa Airlines has the best performance for on-time direct flights from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY), with an on-time rating of 96%. Use the Expedia App to look up your flight schedule before you head off and get real-time alerts about any changes.
What is the best time to fly from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY)?
Book a flight from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Matecana Intl. Airport (PEI)?
If you're on a direct flight from Matecana Intl. Airport (PEI) to Panama City, Tocumen Intl. Airport (PTY) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY) last-minute?
Booking your ticket from PEI to PTY right before your journey is generally more expensive. However, if there's some wiggle room with your departure dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a PEI to PTY flight and hotel package?
Compared with arranging hotels and flights separately, booking a PEI to PTY flight and hotel package with Expedia could result in significant savings. Better still, having everything in one easy place will take the stress out of travel planning. Simply pick your flights and select from our extensive range of stays, then customize your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Matecana Intl. Airport (PEI) to Tocumen Intl. Airport (PTY)?
In most instances, you can modify or cancel your PEI to PTY flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you need further details, head to our Customer Service portal.

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*Available to One Key members.