$427 Cheap Flights from Pisa (PSA) to Columbus (CMH)

View $427 flight on Mon, Apr 13, 2026Opens in a new window

Popular airlines from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH)

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Cheap Flights from Pisa to Columbus (PSA-CMH)

Prices were available within the past 7 days and start at $427 for one-way flights and $1,470 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,470 Roundtrip, found 2 days ago
$1,470
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,470 found 2 days ago
KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,478 Roundtrip, found 2 days ago
$1,478
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,478 found 2 days ago
KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,480 Roundtrip, found 2 days ago
$1,480
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,480 found 2 days ago
KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,481 Roundtrip, found 2 days ago
$1,481
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,481 found 2 days ago
KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,564 Roundtrip, found 2 days ago
$1,564
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,564 found 2 days ago
KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,572 Roundtrip, found 2 days ago
$1,572
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,572 found 2 days ago
KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,574 Roundtrip, found 2 days ago
$1,574
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,574 found 2 days ago
KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,575 Roundtrip, found 2 days ago
$1,575
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,575 found 2 days ago
KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,618 Roundtrip, found 2 days ago
$1,618
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,618 found 2 days ago
KLM
Sun, Nov 16 - Sun, Nov 23
PSA
Pisa
CMH
Columbus
$1,619 Roundtrip, found 2 days ago
$1,619
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Nov 16 from Pisa to Columbus, returning Sun, Nov 23, priced at $1,619 found 2 days ago

Frequently asked questions

How much does a flight from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH) cost?
Lock in a cheap one-way flight from $427 or cheap return flight from $1,470 from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH)?
The cheapest month to fly from PSA to CMH is November, when there's less demand. Off-peak season is often when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH)?
To find the cheapest airline that'll fly you from PSA to CMH, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH)?
You'll need to book a flight with a layover when traveling from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from PSA to CMH?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change depending on a number of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH)?
To avoid potential delays on the Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH) route, aim to travel before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH) last-minute?
Last-minute fares from PSA to CMH are usually more expensive. To secure the best rates, start looking for flights ahead of time. That being said, if you're flexible with your travel plans, it's possible to score a cheap fare right before you leave.
Is it cheaper to book a PSA to CMH flight and hotel package?
Compared with arranging hotels and flights separately, booking a PSA to CMH flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place takes the hassle out of travel planning. Just secure your flights and choose from our extensive range of stays, then personalize your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Galileo Galilei Airport (PSA) to John Glenn Columbus Intl. Airport (CMH)?
It's generally possible to reschedule or cancel your PSA to CMH flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Galileo Galilei
Destination airport
John Glenn Columbus Intl.
Roundtrip price
$1,470
Distance
4535 mi

Book with confidence

Pisa to Columbus Flights

The cheapest times to fly from Pisa to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pisa to Columbus are during the month of November. You can find some of the cheapest flights from Pisa to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pisa to Columbus

Sunday is one of the best days to book for cheap flights from Pisa to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pisa to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pisa to Columbus in 2025. You can also book with separate airlines for your outbound and return journeys, from $427 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pisa to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pisa to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Pisa to Columbus Flights

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*Available to One Key members.