$123 Cheap Flights from Panama City (PTY) to Cali (CLO)

View $123 flight on Sun, Jan 18, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)

Cheap Flights from Panama City to Cali (PTY-CLO)

Prices were available within the past 7 days and start at $123 for one-way flights and $202 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sun, Jan 18 - Mon, Jan 26
PTY
Panama City
CLO
Cali
$202 Roundtrip, just found
$202
Roundtrip
just found
Select Copa flight, departing Sun, Jan 18 from Panama City to Cali, returning Mon, Jan 26, priced at $202 just found
Copa
Thu, Nov 20 - Sun, Nov 23
PTY
Panama City
CLO
Cali
$224 Roundtrip, found 12 hours ago
$224
Roundtrip
found 12 hours ago
Select Copa flight, departing Thu, Nov 20 from Panama City to Cali, returning Sun, Nov 23, priced at $224 found 12 hours ago
Copa
Mon, Dec 15 - Thu, Jan 15
PTY
Panama City
CLO
Cali
$261 Roundtrip, just found
$261
Roundtrip
just found
Select Copa flight, departing Mon, Dec 15 from Panama City to Cali, returning Thu, Jan 15, priced at $261 just found
Copa
Sun, Dec 28 - Tue, Jan 20
PTY
Panama City
CLO
Cali
$262 Roundtrip, found 4 days ago
$262
Roundtrip
found 4 days ago
Select Copa flight, departing Sun, Dec 28 from Panama City to Cali, returning Tue, Jan 20, priced at $262 found 4 days ago
Copa
Thu, Nov 20 - Sun, Nov 23
PTY
Panama City
CLO
Cali
$272 Roundtrip, found 12 hours ago
$272
Roundtrip
found 12 hours ago
Select Copa flight, departing Thu, Nov 20 from Panama City to Cali, returning Sun, Nov 23, priced at $272 found 12 hours ago
avianca
Mon, Dec 15 - Thu, Jan 15
PTY
Panama City
CLO
Cali
$273 Roundtrip, just found
$273
Roundtrip
just found
Select avianca flight, departing Mon, Dec 15 from Panama City to Cali, returning Thu, Jan 15, priced at $273 just found
Copa
Tue, Nov 4 - Fri, Nov 14
PTY
Panama City
CLO
Cali
$275 Roundtrip, found 18 hours ago
$275
Roundtrip
found 18 hours ago
Select Copa flight, departing Tue, Nov 4 from Panama City to Cali, returning Fri, Nov 14, priced at $275 found 18 hours ago
Copa
Mon, Dec 15 - Thu, Jan 15
PTY
Panama City
CLO
Cali
$280 Roundtrip, just found
$280
Roundtrip
just found
Select Copa flight, departing Mon, Dec 15 from Panama City to Cali, returning Thu, Jan 15, priced at $280 just found
Copa
Thu, Nov 20 - Sun, Nov 23
PTY
Panama City
CLO
Cali
$283 Roundtrip, found 12 hours ago
$283
Roundtrip
found 12 hours ago
Select Copa flight, departing Thu, Nov 20 from Panama City to Cali, returning Sun, Nov 23, priced at $283 found 12 hours ago
Aeromexico
Tue, Dec 2 - Sat, Dec 13
PTY
Panama City
CLO
Cali
$351 Roundtrip, found 1 day ago
$351
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Tue, Dec 2 from Panama City to Cali, returning Sat, Dec 13, priced at $351 found 1 day ago

Find the cheapest month to fly from Panama City (PTY) to Cali (CLO)

May is typically the cheapest month to fly

From $221 - $356 per traveler.

Alternative airports near Cali

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Alfonso Bonilla Aragon Intl. CLO. Cheapest and Closest option available. Average driving time to city center is 27 minutes. Flights from $275
CLO
Alfonso Bonilla Aragon Intl.
CheapestClosest
Average driving time to city center27 min
Flights from $275
Flights from Panama City (PTY) to Cali (CLO)
Origin airport
Tocumen Intl.
Destination airport
Alfonso Bonilla Aragon Intl.
Airlines serving
Copa, avianca
Roundtrip price
$201
Distance
434 mi
Average flight time
1 hour 41 mins

Panama City to Cali Flights

The cheapest times to fly from Panama City to Cali

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Cali are during the month of January. You can find some of the cheapest flights from Panama City to Cali with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Cali

Sunday is one of the best days to book for cheap flights from Panama City to Cali: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Cali

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Cali in 2025. You can also book with separate airlines for your outbound and return journeys, from $123 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Cali flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Cali airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO) cost?
Snag a cheap one-way flight from $123 or cheap return flight from $202 from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Flying in January may help you find better deals, as it's the cheapest month for flights between PTY and CLO. You'll often find the lowest prices during off-peak months.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Jump on a nonstop flight with Copa Airlines and fly straight from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO).
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
To find the cheapest airline that'll fly you from PTY to CLO, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Every day on average, 3 direct flights operate from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO). Choose the departure that works for you.
What are the most popular departure times for flights from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
More people fly between PTY and CLO at 3 PM than at any other time. Rather skip the crowds? Try choosing a quieter departure window and you could save on your ticket as well.
What day of the week has the most flights from PTY to CLO?
Thursday has the most flights from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO). Consider taking off on this day and you'll have the best chance of finding a departure that works with your plans.
What is the earliest flight from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Tocumen Intl. Airport (PTY)'s earliest flight to Alfonso Bonilla Aragon Intl. Airport (CLO) leaves at approximately 9:12AM UTC-5. With a flight time of 1h 41m, you'll land at around 10:53AM UTC-5.
How long does it take to fly from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
It takes about 1 hour and 40 minutes to travel the 430 mi from PTY to CLO.
What airline has the least delays from PTY to CLO?
Consider traveling with Copa Airlines if you'd like to go straight from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO) without any interruptions. This airline has the best track record for punctuality, with an on-time score of 88%. Want real-time updates? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
To avoid potential delays on the Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO) route, aim to fly before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Cali from Tocumen Intl. Airport (PTY)?
Check out your flight options from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO). This is the only airport in Cali you can arrive at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO) last-minute?
Waiting until just before your departure to book a flight from PTY to CLO generally means paying more. While you may come across some last-minute discounts, they aren't always guaranteed. Be flexible with your itinerary for a better chance of landing a bargain.
Is it cheaper to book a PTY to CLO flight and hotel package?
Opting for a PTY to CLO flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our extensive range of accommodations and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Typically, it's possible to cancel or reschedule your PTY to CLO flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.