$494 Cheap Flights from Panama City (PTY) to Hermosillo (HMO)

View $494 flight on Thu, Jan 29, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Hermosillo, Sonora (HMO-General Ignacio Pesqueira Garcia Intl.)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Panama City to Hermosillo (PTY-HMO)

Prices were available within the past 7 days and start at $494 for one-way flights and $698 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Mon, Feb 16 - Mon, Mar 2
PTY
Panama City
HMO
Hermosillo
$698 Roundtrip, found 8 hours ago
$698
Roundtrip
found 8 hours ago
Select Aeromexico flight, departing Mon, Feb 16 from Panama City to Hermosillo, returning Mon, Mar 2, priced at $698 found 8 hours ago
Aeromexico
Mon, Feb 16 - Mon, Mar 2
PTY
Panama City
HMO
Hermosillo
$703 Roundtrip, found 8 hours ago
$703
Roundtrip
found 8 hours ago
Select Aeromexico flight, departing Mon, Feb 16 from Panama City to Hermosillo, returning Mon, Mar 2, priced at $703 found 8 hours ago
Aeromexico
Mon, Feb 16 - Mon, Mar 2
PTY
Panama City
HMO
Hermosillo
$704 Roundtrip, found 8 hours ago
$704
Roundtrip
found 8 hours ago
Select Aeromexico flight, departing Mon, Feb 16 from Panama City to Hermosillo, returning Mon, Mar 2, priced at $704 found 8 hours ago
Copa
Tue, Dec 16 - Tue, Feb 3
PTY
Panama City
HMO
Hermosillo
$730 Roundtrip, found 4 days ago
$730
Roundtrip
found 4 days ago
Select Copa flight, departing Tue, Dec 16 from Panama City to Hermosillo, returning Tue, Feb 3, priced at $730 found 4 days ago
Copa
Mon, Feb 16 - Mon, Mar 2
PTY
Panama City
HMO
Hermosillo
$737 Roundtrip, found 8 hours ago
$737
Roundtrip
found 8 hours ago
Select Copa flight, departing Mon, Feb 16 from Panama City to Hermosillo, returning Mon, Mar 2, priced at $737 found 8 hours ago
Aeromexico
Thu, Mar 12 - Mon, Mar 16
PTY
Panama City
HMO
Hermosillo
$748 Roundtrip, found 4 days ago
$748
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Thu, Mar 12 from Panama City to Hermosillo, returning Mon, Mar 16, priced at $748 found 4 days ago
Aeromexico
Fri, Mar 13 - Mon, Mar 16
PTY
Panama City
HMO
Hermosillo
$806 Roundtrip, found 5 days ago
$806
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Fri, Mar 13 from Panama City to Hermosillo, returning Mon, Mar 16, priced at $806 found 5 days ago
Aeromexico
Thu, Dec 18 - Mon, Feb 2
PTY
Panama City
HMO
Hermosillo
$832 Roundtrip, found 4 days ago
$832
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Thu, Dec 18 from Panama City to Hermosillo, returning Mon, Feb 2, priced at $832 found 4 days ago
Aeromexico
Mon, Feb 16 - Mon, Mar 2
PTY
Panama City
HMO
Hermosillo
$840 Roundtrip, found 8 hours ago
$840
Roundtrip
found 8 hours ago
Select Aeromexico flight, departing Mon, Feb 16 from Panama City to Hermosillo, returning Mon, Mar 2, priced at $840 found 8 hours ago
American Airlines
Mon, Feb 16 - Mon, Mar 2
PTY
Panama City
HMO
Hermosillo
$926 Roundtrip, found 8 hours ago
$926
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Feb 16 from Panama City to Hermosillo, returning Mon, Mar 2, priced at $926 found 8 hours ago

Alternative airports near Hermosillo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to General Ignacio Pesqueira Garcia Intl. HMO. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $949
HMO
General Ignacio Pesqueira Garcia Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $949
Flights from Panama City (PTY) to Hermosillo (HMO)
Origin airport
Tocumen Intl.
Destination airport
General Ignacio Pesqueira Garcia Intl.
Airlines serving
Aeromexico, American Airlines, Copa
Roundtrip price
$697
Distance
2473 mi

Panama City to Hermosillo Flights

The cheapest times to fly from Panama City to Hermosillo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Hermosillo are during the month of February. You can find some of the cheapest flights from Panama City to Hermosillo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Hermosillo

Sunday is one of the best days to book for cheap flights from Panama City to Hermosillo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Hermosillo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Hermosillo in 2026. You can also book with separate airlines for your outbound and return journeys, from $494 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Hermosillo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Hermosillo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO) cost?
Grab a cheap one-way flight from $494 or cheap return flight from $698 from Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO)?
The cheapest month to fly from PTY to HMO is February, when there's less demand. Off-peak season is typically when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO)?
To find the cheapest airline that'll fly you from PTY to HMO, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO)?
There aren't any daily direct flights from Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO). But you can choose flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from PTY to HMO?
Usually you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can change depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO)?
To avoid potential delays on the Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO) route, travel before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO) last-minute?
Last-minute bookings from PTY to HMO are typically more expensive. To lock in the lowest rates, start looking for flights well in advance. That being said, if your travel plans are flexible, you may land a cheap fare just before your departure.
Is it cheaper to book a PTY to HMO flight and hotel package?
You'll typically save money by securing a PTY to HMO flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After selecting your ideal accommodations and flights, consider adding extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to General Ignacio Pesqueira Garcia Intl. Airport (HMO)?
In most cases, you can cancel or reschedule your PTY to HMO flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you want more information, go to our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.