
Popular airlines from Santiago Intl. Airport (SCL) to Las Americas Intl. Airport (SDQ)
- Avianca
Avianca
- Copa
Copa
- Delta
Delta
- American Airlines
American Airlines
- United
United
- Aeromexico
Aeromexico
- British Airways
British Airways
- Plan, book, fly with confidence
trending down icon Be in the knowGet alerts if flight prices drop or rise*bex rewards loyalty icon Book smarterSave up to 30% on select hotels after you book a flight*one key icon
Cheap Flights from Santiago to Santo Domingo (SCL-SDQ)
Prices were available within the past 7 days and start at $213 for one-way flights and $480 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Find the cheapest month to fly from Santiago (SCL) to Santo Domingo (SDQ)
September is typically the cheapest month to fly
Graph displaying average flight prices per month
Alternative airports near Santo Domingo
Prices were available within the past 7 days. Prices and availability are subject to change.
Origin airport | Arturo Merino Benitez |
Destination airport | Las Americas Intl. |
Airlines serving | Aeromexico, American Airlines, BEK AIR, British Airways, Copa, Delta, United, avianca |
Roundtrip price | $479 |
Distance | 3581 mi |
Santiago to Santo Domingo Flights
The cheapest times to fly from Santiago to Santo Domingo
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Santo Domingo are during the month of October. You can find some of the cheapest flights from Santiago to Santo Domingo with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Santiago to Santo Domingo
Sunday is one of the best days to book for cheap flights from Santiago to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Santiago to Santo Domingo
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $213 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently asked questions
Explore a world of travel with Expedia
Top Routes from Santiago
- Santiago to Newark Liberty Intl. Airport (SCL - EWR)
- Santiago to Los Angeles (SCL - LAX)
- Santiago to Miami (SCL - MIA)
- Santiago to Rio de Janeiro (SCL - GIG)
- Santiago to Punta Cana (SCL - PUJ)
- Santiago to Rio de Janeiro (SCL - SDU)
- Santiago to New York (SCL - LGA)
- Santiago to Florianópolis (SCL - FLN)
- Santiago to Buenos Aires (SCL - AEP)
- Santiago to Barcelona (SCL - BCN)
- Santiago to Punta Arenas (SCL - PUQ)
- Santiago to New York (SCL - JFK)
Top Routes to Santo Domingo
- Chicago to Santo Domingo (ORD - SDQ)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- Los Angeles to Santo Domingo (LAX - SDQ)
- Washington to Santo Domingo (DCA - SDQ)
- Miami to Santo Domingo (MIA - SDQ)
- Tampa to Santo Domingo (TPA - SDQ)
- New York to Santo Domingo (LGA - SDQ)
- Boston to Santo Domingo (BOS - SDQ)
- Fort Lauderdale to Santo Domingo (FLL - SDQ)
- Charlotte to Santo Domingo (CLT - SDQ)
- Washington to Santo Domingo (IAD - SDQ)
- New York to Santo Domingo (JFK - SDQ)
Top Flight Destinations
- Flights to Punta Cana
- Flights to Puerto Plata
- Flights to Santo Domingo
- Flights to La Romana
- Flights to Sosúa
- Flights to Las Terrenas
- Flights to Santiago de los Caballeros
- Flights to Samaná
- Flights to Miches
- Flights to Guayacanes
- Flights to Barahona
- Flights to Higuey
- Flights to Monte Cristi
- Flights to Pedernales
- Flights to Rio San Juan
- Flights to Bonao
- Flights to Villa Isabela
- Flights to Punta Rucia
- Flights to Cabrera
- Flights to Constanza
Expedia's Latest Trends
- Washington (DCA) to San Juan (SJU) Flights
- Miami (MIA) to San Juan (SJU) Flights
- Kingston (KIN) to New York (JFK) Flights
- Tampa (TPA) to San Juan (SJU) Flights
- Hartford (BDL) to San Juan (SJU) Flights
- Dallas (DFW) to San Juan (SJU) Flights
- Los Angeles (LAX) to San Juan (SJU) Flights
- New York (JFK) to San Juan (SJU) Flights
- Charlotte (CLT) to San Juan (SJU) Flights
- Fort Lauderdale (FLL) to San Juan (SJU) Flights
- Philadelphia (PHL) to San Juan (SJU) Flights
- New York (JFK) to Kingston (KIN) Flights
- Atlanta (ATL) to San Juan (SJU) Flights
- New York (JFK) to Santo Domingo (SDQ) Flights
- Newark Liberty Intl. Airport (EWR) to San Juan (SJU) Flights
- Boston (BOS) to San Juan (SJU) Flights
- Kingston (KIN) to Fort Lauderdale (FLL) Flights
- New York (NYC) to San Juan (SJU) Flights
- San Juan (SJU) to St. Thomas (STT) Flights
- Detroit (DTW) to San Juan (SJU) Flights
- Miami (MIA) to Santo Domingo (SDQ) Flights
- Boston (BOS) to Santo Domingo (SDQ) Flights
- Chicago (ORD) to San Juan (SJU) Flights
- Minneapolis (MSP) to San Juan (SJU) Flights
- Raleigh (RDU) to San Juan (SJU) Flights
- Orlando (MCO) to San Juan (SJU) Flights
- Baltimore (BWI) to San Juan (SJU) Flights
- Kingston (KIN) to Panama City (PTY) Flights
- Houston (IAH) to San Juan (SJU) Flights
- San Juan (SJU) to Orlando (MCO) Flights