Cheap Flights from Knoxville (TYS) to Destin (DSI)

Popular airlines from McGhee Tyson Airport (TYS) to Destin-Fort Walton Beach Airport (DSI)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Alternative airports near Destin

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Northwest Florida Regional VPS. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $535
VPS
Northwest Florida Regional
Cheapest
Average driving time to city center29 min
Flights from $535

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Destin-Fort Walton Beach Airport (DSI) cost?
Grab a cheap one-way flight or cheap return flight from McGhee Tyson Airport (TYS) to Destin-Fort Walton Beach Airport (DSI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Destin-Fort Walton Beach Airport (DSI)?
The cheapest month to fly from TYS to DSI is , when there's less demand. Off-peak months are generally when airlines offer better prices between these airports.
How many flights per day from McGhee Tyson Airport (TYS) to Destin-Fort Walton Beach Airport (DSI)?
Direct flights from McGhee Tyson Airport (TYS) to Destin-Fort Walton Beach Airport (DSI) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYS to DSI?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Destin-Fort Walton Beach Airport (DSI)?
To arrive at Destin-Fort Walton Beach Airport (DSI) without delays, pick a flight that leaves McGhee Tyson Airport (TYS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Destin-Fort Walton Beach Airport (DSI) last-minute?
Last-minute fares from TYS to DSI are typically more expensive. To lock in the lowest prices, start searching for flights as soon as possible. That being said, if you're flexible with your travel dates, you may find a cheap fare right before your journey.
Is it cheaper to book a TYS to DSI flight and hotel package?
Booking a TYS to DSI flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Select from our wide range of stays and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Destin-Fort Walton Beach Airport (DSI)?
It's generally possible to cancel or reschedule your TYS to DSI flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
McGhee Tyson
Destination airport
Destin-Fort Walton Beach
Distance
400 mi

Book with confidence

Knoxville to Destin Flights

The cheapest times to fly from Knoxville to Destin

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Destin are during the month of . You can find some of the cheapest flights from Knoxville to Destin with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Destin

Sunday is one of the best days to book for cheap flights from Knoxville to Destin: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Destin

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Destin in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Destin flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Destin airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Destin Flights

Explore a world of travel with Expedia

*Available to One Key members.