$166 Cheap Flights from Manzanillo (ZLO) to Reynosa (REX)

View $166 flight on Fri, Dec 19, 2025Opens in a new window

Popular airlines from Manzanillo, Colima (ZLO-Playa de Oro Intl.) to Reynosa, Tamaulipas (REX-General Lucio Blanco Intl.)

Cheap Flights from Manzanillo to Reynosa (ZLO-REX)

Prices were available within the past 7 days and start at $166 for one-way flights and $255 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Mon, Dec 1 - Mon, Dec 8
ZLO
Manzanillo
REX
Reynosa
$255 Roundtrip, found 4 days ago
$255
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Mon, Dec 1 from Manzanillo to Reynosa, returning Mon, Dec 8, priced at $255 found 4 days ago
Aeromexico
Mon, Dec 1 - Mon, Dec 8
ZLO
Manzanillo
REX
Reynosa
$342 Roundtrip, found 4 days ago
$342
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Mon, Dec 1 from Manzanillo to Reynosa, returning Mon, Dec 8, priced at $342 found 4 days ago
Aeromexico
Mon, Dec 1 - Mon, Dec 8
ZLO
Manzanillo
REX
Reynosa
$430 Roundtrip, found 4 days ago
$430
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Mon, Dec 1 from Manzanillo to Reynosa, returning Mon, Dec 8, priced at $430 found 4 days ago

Frequently asked questions

How much does a flight from Playa de Oro Intl. Airport (ZLO) to General Lucio Blanco Intl. Airport (REX) cost?
Secure a cheap one-way flight from $166 or cheap return flight from $255 from Playa de Oro Intl. Airport (ZLO) to General Lucio Blanco Intl. Airport (REX) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Playa de Oro Intl. Airport (ZLO) to General Lucio Blanco Intl. Airport (REX)?
Traveling in December can help you save, as it's the cheapest month for flights between ZLO and REX. You'll usually find the lowest prices during off-peak months.
What is the cheapest airline that flies from Playa de Oro Intl. Airport (ZLO) to General Lucio Blanco Intl. Airport (REX)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll fly you from ZLO to REX. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Playa de Oro Intl. Airport (ZLO) to General Lucio Blanco Intl. Airport (REX)?
There are no daily direct flights departing from Playa de Oro Intl. Airport (ZLO) to General Lucio Blanco Intl. Airport (REX). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be on your way in no time.
What day of the week has the most flights from ZLO to REX?
Generally you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can change depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Playa de Oro Intl. Airport (ZLO) to General Lucio Blanco Intl. Airport (REX)?
To land at General Lucio Blanco Intl. Airport (REX) on schedule, opt for a flight that takes off from Playa de Oro Intl. Airport (ZLO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Playa de Oro Intl. Airport (ZLO) to General Lucio Blanco Intl. Airport (REX) last-minute?
Last-minute bookings from ZLO to REX are generally more expensive. For the lowest rates, start searching for flights as early as possible. That said, if you're flexible with your travel dates, you may score a cheap ticket right before you leave.
Is it cheaper to book a ZLO to REX flight and hotel package?
You'll typically save money by booking a ZLO to REX flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. After choosing your ideal accommodations and flights, consider adding extras like activities, car rentals and tours.
Can I cancel or change the date of my flight from Playa de Oro Intl. Airport (ZLO) to General Lucio Blanco Intl. Airport (REX)?
In most instances, you can cancel or modify your ZLO to REX flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want more information, go to our Customer Service portal.

Travel information

Origin airport
Playa de Oro Intl.
Destination airport
General Lucio Blanco Intl.
Roundtrip price
$254
Distance
622 mi

Book with confidence

Manzanillo to Reynosa Flights

The cheapest times to fly from Manzanillo to Reynosa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Manzanillo to Reynosa are during the month of December. You can find some of the cheapest flights from Manzanillo to Reynosa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Manzanillo to Reynosa

Sunday is one of the best days to book for cheap flights from Manzanillo to Reynosa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Manzanillo to Reynosa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Manzanillo to Reynosa in 2025. You can also book with separate airlines for your outbound and return journeys, from $166 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Manzanillo to Reynosa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Manzanillo to Reynosa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Manzanillo to Reynosa Flights

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*Available to One Key members.