$169 Cheap American Airlines flights Lexington (LEX) to Charlotte (CLT)

You can find cheap round-trip American Airlines flights from $347 from LEX to CLT by sorting your results from "Price (lowest to highest)" on Expedia. Or look for deals from $169 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Begin your search one to three months ahead of your departure date to find cheap fares on American Airlines flights from Blue Grass Airport (LEX) to Charlotte-Douglas Intl. Airport (CLT). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Time it well, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Departing LEX at 6:25AM UTC-5, the first American Airlines flight to CLT lands at 8:04AM UTC-5. Flying early means you're less likely to encounter cancellations or delays.* Don't like early starts? The last American Airlines flight from LEX to CLT departs at 8:09PM UTC-5 and touches down at 9:41PM UTC-5.*Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.