$64 Cheap American Airlines flights New York (LGA) to Tampa (TPA)

Finding cheap one-way American Airlines flights from LGA to TPA from $64 on Expedia is a cinch — just filter by "Price (lowest to highest)." Alternatively, check out our affordable return fares from $127 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Begin your search one to three months ahead of your travel date to get cheap fares on American Airlines flights from LaGuardia Airport (LGA) to Tampa Intl. Airport (TPA). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest flight from LGA to TPA with American Airlines departs at 10:45AM UTC-5. You'll land at 1:45PM UTC-5. The final American Airlines flight of the day leaves at 6:30PM UTC-5 and arrives at 9:33PM UTC-5. With 20% fewer cancellations for morning and mid-morning departures, starting your travel day early is generally the smartest choice.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.