$112 Cheap American Airlines flights St. Louis (STL) to Tampa (TPA)

Finding cheap one-way American Airlines flights from STL to TPA from $112 on Expedia is a cinch — just filter by “Price (lowest to highest).” Alternatively, check out our affordable return fares from $216 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to Tampa are often cheaper in the low-season months of September and November. Whether you’re after a one-way or a return ticket, you could find a better deal then.

Start searching one to three months ahead of your travel date to find cheaper fares on American Airlines flights from Lambert-St. Louis Intl. Airport (STL) to Tampa Intl. Airport (TPA). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To see if there’s a direct route from STL to TPA with American Airlines or any other carriers, select the “Nonstop” filter when looking for flights.

Search American Airlines’s earliest flights from STL to TPA by selecting our “Early Morning” and “Morning” filters. Not only will you get to where you’re going sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Tampa Intl. Airport (TPA) is the primary Tampa gateway for American Airlines flights from Lambert-St. Louis Intl. Airport (STL).

Changes are typically free within 24 hours of booking, but your airline may charge a fee after that. For more information about modifying your flights, head to your “Trips,” select your flight and click on “Manage Booking.” If you’d like the flexibility to change your plans without extra charges, check the “Changes included” and “No cancel fee” filters when organizing your next escape.