$119 Cheap American Airlines flights Manchester (MHT) to Charleston (CHS)

You can find budget-friendly return American Airlines flights from $159 from MHT to CHS by filtering your results from "Price (lowest to highest)" on Expedia. Or search for options from $119 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find cheap American Airlines fares from Manchester-Boston Regional Airport (MHT) to Charleston Intl. Airport (CHS), start searching one to three months before your planned departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact the cost. Sunday is typically the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by choosing to book on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to see the earliest flights from MHT to CHS. Setting off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.