$3,069 Cheap American Airlines flights Manchester (MAN) to Charleston (CHS)

Landing cheap one-way American Airlines flights from MAN to CHS from $3,069 on Expedia is a cinch --- just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly return fares from $882 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Snagging the best American Airlines deals from MAN to CHS often comes down to timing. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. As an added bonus, you can pocket 17% on average by buying your fare on a Sunday compared to a Friday, which is often the most expensive day to book.* It's a good idea to start checking out flights about one month before you plan to travel.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departures from MAN to CHS with American Airlines, filter your search by "Morning" and "Early Morning." Choosing an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.