$107 Cheap American Airlines flights Minneapolis (MSP) to Harlingen (HRL)

Finding cheap one-way American Airlines flights from MSP to HRL from $107 on Expedia is a breeze — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly return fares from $180 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the most affordable months to travel to Harlingen with American Airlines. You could also find fantastic deals on return and one-way fares in September.

Start searching one to three months before your departure to score cheaper fares on American Airlines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Valley Intl. Airport (HRL). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Time it well, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To figure out if there’s a direct journey from MSP to HRL with American Airlines or other airlines, select the “Nonstop” filter when looking for flights.

Filter your results by “Early Morning” and “Morning” to see the earliest flights from MSP to HRL. Heading off early means you’re 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Harlingen come in to land at Valley Intl. Airport (HRL). This is the main gateway here.

Depending on the ticket type you purchased, a fee generally applies if you change or cancel your booking more than 24 hours after it’s confirmed. To secure flexible plane tickets, select our “No cancel fee” or “Changes included” filter while searching for flights. For more information on canceling or changing your reservation, visit “Trips,” select your flight and click on “Manage Booking.”