$164 Cheap American Airlines flights Philadelphia (PHL) to Greenville (GSP)

Use the "Price (lowest to highest)" filter on Expedia to search for cheap American Airlines round-trip flights from $291 from PHL to GSP. Affordable one-way options from $164 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable American Airlines flights from Philadelphia Intl. Airport (PHL) to Greenville-Spartanburg Intl. Airport (GSP) one to three months prior to your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and journey, the best day to book a domestic flight is generally Sunday and the most expensive day tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Jetting off from PHL at 8:30AM UTC-5, the first American Airlines flight to GSP arrives at 10:43AM UTC-5. Flying early means you're less likely to experience delays.* Prefer to travel later? The last American Airlines flight from PHL to GSP departs at 6:31PM UTC-5 and touches down at 8:30PM UTC-5.*Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.