$126 Cheap American Airlines flights Sioux Falls (FSD) to Charlotte (CLT)

Set the "Price (lowest to highest)" filter on Expedia to find cheap American Airlines round-trip flights from $255 from FSD to CLT. Affordable one-way fares from $126 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable American Airlines flights from Sioux Falls Regional Airport (FSD) to Charlotte-Douglas Intl. Airport (CLT) one to three months before your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and itinerary, the ideal day to book a domestic flight is generally Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from FSD to CLT with American Airlines, filter your results by "Early Morning" and "Morning." Choosing an early flight generally means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.