$353 Cheap American Airlines flights Waco (ACT) to Columbus (CMH)

Landing cheap one-way American Airlines flights from ACT to CMH from $353 on Expedia is a cinch — just filter by "Price (lowest to highest)." Alternatively, check out our affordable round-trip fares from $400 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

For cheap American Airlines fares from Waco Regional Airport (ACT) to John Glenn Columbus Intl. Airport (CMH), start searching one to three months before your intended departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the overall cost. Sunday is generally the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your trip on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Browse American Airlines's earliest flights from ACT to CMH by selecting the "Early Morning" and "Morning" filters. Not only will you get to where you're going sooner, early departures are also 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.