$551 Cheap Copa flights Mexico City (MEX) to Panama City (PTY)

Set the "Price (lowest to highest)" filter on Expedia to find cheap Copa Airlines round-trip flights from $353 from MEX to PTY. Affordable one-way options from $551 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find affordable flights from MEX to PTY with Copa Airlines, begin your search about one month before your intended departure. You can save 17% when you book your international tickets 18 to 29 days ahead instead of booking four to five months in advance. Want another tip? Booking on Sunday can lead to average savings of 17% compared to Friday (the most expensive day).**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Departing MEX at 1:20AM UTC-6, the earliest Copa Airlines flight to PTY arrives at 5:58AM UTC-5. Traveling early means you'll be less likely to encounter delays.* Prefer a later start? The last Copa Airlines flight from MEX to PTY departs at 3:30PM UTC-6 and touches down at 8:08PM UTC-5.*Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.