$125 Cheap Delta flights Lexington (LEX) to Buffalo (BUF)

Scoring cheap one-way Delta Air Lines flights from LEX to BUF from $125 on Expedia is easy — just filter by "Price (lowest to highest)." Alternatively, check out our affordable return fares from $229 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your departure date to score cheaper fares on Delta Air Lines flights from Blue Grass Airport (LEX) to Buffalo Niagara Intl. Airport (BUF). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Search Delta Air Lines's earliest flights from LEX to BUF by selecting our "Early Morning" and "Morning" filters. Not only will you arrive sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Delta Air Lines makes flying from LEX to BUF enjoyable with an excellent in-flight experience and a rewarding loyalty program. You could even start earning points with Delta SkyMiles. Make sure you sign up to Expedia's free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future bookings.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.