$115 Cheap Delta flights Columbia (CAE) to Chicago (MDW)

Landing cheap one-way Delta Air Lines flights from CAE to MDW from $115 on Expedia is simple — just filter by "Price (lowest to highest)." Or check out our affordable return fares from $229 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

For cheap Delta Air Lines fares from Columbia Metropolitan Airport (CAE) to Midway Intl. Airport (MDW), start searching one to three months before your planned departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact the overall cost. Sunday is typically the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Browse Delta Air Lines's earliest flights from CAE to MDW by checking our "Early Morning" and "Morning" filters. Not only will you arrive at your destination sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Traveling from CAE to MDW with Delta Air Lines means enjoying a variety of perks, including an excellent in-flight experience and a rewarding loyalty program. Plus, when booking through Expedia, One Key™ members can earn OneKeyCash™* to redeem on select future travel purchases. That's on top of the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.