$112 Cheap Delta flights Des Moines (DSM) to Indianapolis (IND)

Grab cheap round-trip Delta Air Lines flights from $223 from DSM to IND by sorting your results from "Price (lowest to highest)" on Expedia. Or search for bargains from $112 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find cheap Delta Air Lines fares from Des Moines Intl. Airport (DSM) to Indianapolis Intl. Airport (IND), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect how much you pay. Sunday is usually the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your journey on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Browse Delta Air Lines's earliest flights from DSM to IND by using our "Morning" and "Early Morning" filters. Not only will you get to your destination sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Offering a rewarding loyalty program and an excellent in-flight experience, Delta Air Lines is a favorite for many travelers flying from DSM to IND. Plus, if you're a Delta SkyMiles and One Key™ member booking with Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can be spent on future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.