$1,573 Cheap Delta flights Palermo (PMO) to Charleston (CHS)

Set the "Price (lowest to highest)" filter on Expedia to search for cheap Delta Air Lines round-trip flights from PMO to CHS. Affordable one-way tickets from $1,573 are available as well.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for Delta Air Lines flights from PMO to CHS about one month before you want to go. The most affordable time to reserve an international flight is generally 18 to 29 days ahead of your travel date when you can save 17% versus booking four to five months in advance. No matter your itinerary and fare class, the best day of the week to book international airfare is usually Sunday. Friday is often the most expensive. Travelers who book on a Sunday can save 17% on average compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to find the earliest flights from PMO to CHS. Setting off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Delta Air Lines makes traveling from PMO to CHS more enjoyable with a rewarding loyalty program and an excellent in-flight experience. You even have the chance to collect points with Delta SkyMiles. Don't forget to join Expedia's free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future trips.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.