$228 Cheap Delta flights Roanoke (ROA) to Indianapolis (IND)

Finding cheap one-way Delta Air Lines flights from ROA to IND from $228 on Expedia is simple — just filter by "Price (lowest to highest)." Or check out our budget-friendly round-trip fares from $229 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find cheap Delta Air Lines fares from Roanoke Regional Airport (ROA) to Indianapolis Intl. Airport (IND), start searching one to three months before your planned departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact what you pay. Sunday is usually the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departures from ROA to IND with Delta Air Lines, sort your results by "Early Morning" and "Morning." Choosing an early flight generally means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Taking off from ROA to IND with Delta Air Lines comes with a host of perks, including an excellent in-flight experience and a rewarding loyalty program. Plus, when you book through Expedia, One Key™ members can earn OneKeyCash™* to use on select future travel purchases. That's on top of the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.