$238 Cheap Turkish Airlines flights Madrid (MAD) to Istanbul (IST)

Finding cheap one-way Turkish Airlines flights from MAD to IST from $238 on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly return fares from $331 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To grab cheap flights from MAD to IST with Turkish Airlines, begin your search about one month before your intended departure. You can save 17% when you lock in your international tickets 18 to 29 days ahead instead of booking four to five months in advance. Another helpful tip? Booking on Sunday offers average savings of 17% compared to Friday (the most expensive day).**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from MAD to IST with Turkish Airlines, sort your results by "Morning" and "Early Morning." Choosing an early flight generally means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.