$100 Cheap United flights Knoxville (TYS) to New Orleans (MSY)

Scoring cheap one-way United Airlines flights from TYS to MSY from $100 on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Or check out our affordable return fares from $228 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months before your departure to score cheap fares on United Airlines flights from McGhee Tyson Airport (TYS) to Louis Armstrong New Orleans Intl. Airport (MSY). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing right, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Early Morning" and "Morning" to browse the earliest departures from TYS to MSY. Leaving early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Fly from TYS to MSY with United Airlines and enjoy a host of benefits starting with a rewarding loyalty program. When you book through Expedia as a United Mileage Plus and One Key™ member, you could also earn OneKeyCash™* to redeem on select future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.