$163 Cheap Flights from New Orleans (MSY) to Panama City (PTY)

View $163 flight on Wed, Oct 29, 2025Opens in a new window

Popular airlines from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY)

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Cheap Flights from New Orleans to Panama City (MSY-PTY)

Prices were available within the past 7 days and start at $163 for one-way flights and $391 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Oct 29 - Tue, Nov 4
MSY
New Orleans
PTY
Panama City
$391 Roundtrip, found 1 hour ago
$391
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Oct 29 from New Orleans to Panama City, returning Tue, Nov 4, priced at $391 found 1 hour ago
Delta
Wed, Oct 29 - Tue, Nov 4
MSY
New Orleans
PTY
Panama City
$391 Roundtrip, found 1 hour ago
$391
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, Oct 29 from New Orleans to Panama City, returning Tue, Nov 4, priced at $391 found 1 hour ago
United
Wed, Oct 29 - Tue, Nov 4
MSY
New Orleans
PTY
Panama City
$391 Roundtrip, found 1 hour ago
$391
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Oct 29 from New Orleans to Panama City, returning Tue, Nov 4, priced at $391 found 1 hour ago
American Airlines
Wed, Nov 5 - Wed, Nov 26
MSY
New Orleans
PTY
Panama City
$396 Roundtrip, found 9 hours ago
$396
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Wed, Nov 5 from New Orleans to Panama City, returning Wed, Nov 26, priced at $396 found 9 hours ago
United
Sun, Jan 4 - Mon, Jan 19
MSY
New Orleans
PTY
Panama City
$398 Roundtrip, found 2 hours ago
$398
Roundtrip
found 2 hours ago
Select United flight, departing Sun, Jan 4 from New Orleans to Panama City, returning Mon, Jan 19, priced at $398 found 2 hours ago
United
Wed, Oct 29 - Tue, Nov 4
MSY
New Orleans
PTY
Panama City
$398 Roundtrip, found 1 hour ago
$398
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Oct 29 from New Orleans to Panama City, returning Tue, Nov 4, priced at $398 found 1 hour ago
American Airlines
Wed, Oct 29 - Tue, Nov 4
MSY
New Orleans
PTY
Panama City
$400 Roundtrip, found 1 hour ago
$400
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Oct 29 from New Orleans to Panama City, returning Tue, Nov 4, priced at $400 found 1 hour ago
American Airlines
Wed, Nov 26 - Tue, Dec 2
MSY
New Orleans
PTY
Panama City
$402 Roundtrip, found 15 hours ago
$402
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Nov 26 from New Orleans to Panama City, returning Tue, Dec 2, priced at $402 found 15 hours ago
American Airlines
Thu, Dec 11 - Tue, Dec 16
MSY
New Orleans
PTY
Panama City
$405 Roundtrip, found 13 hours ago
$405
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Thu, Dec 11 from New Orleans to Panama City, returning Tue, Dec 16, priced at $405 found 13 hours ago
Delta
Mon, Oct 20 - Tue, Nov 4
MSY
New Orleans
PTY
Panama City
$405 Roundtrip, found 17 hours ago
$405
Roundtrip
found 17 hours ago
Select Delta flight, departing Mon, Oct 20 from New Orleans to Panama City, returning Tue, Nov 4, priced at $405 found 17 hours ago

Find the cheapest month to fly from New Orleans (MSY) to Panama City (PTY)

June is typically the cheapest month to fly

From $371 - $1,006 per traveler.

Graph displaying average flight prices per month

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $477
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $477
Flights from New Orleans (MSY) to Panama City (PTY)
Origin airport
Louis Armstrong New Orleans Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$391
Distance
1606 mi

New Orleans to Panama City Flights

The cheapest times to fly from New Orleans to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from New Orleans to Panama City are during the month of October. You can find some of the cheapest flights from New Orleans to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from New Orleans to Panama City

Sunday is one of the best days to book for cheap flights from New Orleans to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from New Orleans to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from New Orleans to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $163 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap New Orleans to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your New Orleans to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY) cost?
Snag a cheap one-way flight from $163 or cheap return flight from $391 from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY)?
The cheapest month to fly from MSY to PTY is October, when there's less demand. Off-peak months are generally when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MSY to PTY flight.
How many flights per day from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY)?
Direct flights from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MSY to PTY?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from MSY to PTY?
Copa Airlines has the best performance for on-time direct flights from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY), with an on-time rating of 80%. Use the Expedia App to check your flight schedule before you head off and get real-time alerts about any trip changes.
What is the best time to fly from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY)?
Book a flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY) that takes off before 3 PM to reduce the risk of delays and cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY) last-minute?
Booking your flight from MSY to PTY right before your getaway is typically more expensive. But if there's some wiggle room with your schedule, you could snag a cheap last-minute fare.
Is it cheaper to book a MSY to PTY flight and hotel package?
Booking a MSY to PTY flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Select from our impressive range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY)?
In most cases, you can cancel or reschedule your MSY to PTY flight. However, additional charges may apply, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you'd like more details, head to our Customer Service portal.

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*Available to One Key members.