$38 Cheap Flights from Pisa (PSA) to Brussels (BRU)

View $38 flight on Wed, Oct 15, 2025Opens in a new window

Popular airlines from Galileo Galilei Airport (PSA) to Brussels Airport (BRU)

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Cheap Flights from Pisa to Brussels (PSA-BRU)

Prices were available within the past 7 days and start at $38 for one-way flights and $136 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Ryanair
Mon, Oct 20 - Wed, Oct 22
PSA
Pisa
BRU
Brussels
$136 Roundtrip, found 2 days ago
$136
Roundtrip
found 2 days ago
Select Ryanair flight, departing Mon, Oct 20 from Pisa to Brussels, returning Wed, Oct 22, priced at $136 found 2 days ago
Lufthansa
Thu, Jun 11 - Thu, Jun 18
PSA
Pisa
BRU
Brussels
$240 Roundtrip, found 6 days ago
$240
Roundtrip
found 6 days ago
Select Lufthansa flight, departing Thu, Jun 11 from Pisa to Brussels, returning Thu, Jun 18, priced at $240 found 6 days ago
British Airways
Sat, Nov 22 - Mon, Nov 24
PSA
Pisa
BRU
Brussels
$250 Roundtrip, found 1 day ago
$250
Roundtrip
found 1 day ago
Select British Airways flight, departing Sat, Nov 22 from Pisa to Brussels, returning Mon, Nov 24, priced at $250 found 1 day ago
KLM
Mon, Nov 10 - Mon, Nov 24
PSA
Pisa
BRU
Brussels
$346 Roundtrip, found 8 hours ago
$346
Roundtrip
found 8 hours ago
Select KLM flight, departing Mon, Nov 10 from Pisa to Brussels, returning Mon, Nov 24, priced at $346 found 8 hours ago
Air Baltic
Sat, Nov 22 - Mon, Nov 24
PSA
Pisa
BRU
Brussels
$628 Roundtrip, found 1 day ago
$628
Roundtrip
found 1 day ago
Select Air Baltic flight, departing Sat, Nov 22 from Pisa to Brussels, returning Mon, Nov 24, priced at $628 found 1 day ago
Aer Lingus
Thu, Jun 11 - Thu, Jun 18
PSA
Pisa
BRU
Brussels
$652 Roundtrip, found 6 days ago
$652
Roundtrip
found 6 days ago
Select Aer Lingus flight, departing Thu, Jun 11 from Pisa to Brussels, returning Thu, Jun 18, priced at $652 found 6 days ago

Alternative airports near Brussels

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Brussels - National BRU. Cheapest and Closest option available. Average driving time to city center is 15 minutes. Flights from $679
BRU
Brussels - National
CheapestClosest
Average driving time to city center15 min
Flights from $679
Flights from Pisa (PSA) to Brussels (BRU)
Origin airport
Galileo Galilei
Destination airport
Brussels - National
Airlines serving
Air Baltic, British Airways, KLM
Roundtrip price
$136
Distance
568 mi
Average flight time
1 hour 50 mins

Pisa to Brussels Flights

The cheapest times to fly from Pisa to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pisa to Brussels are during the month of October. You can find some of the cheapest flights from Pisa to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pisa to Brussels

Sunday is one of the best days to book for cheap flights from Pisa to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pisa to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pisa to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $38 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pisa to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pisa to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU) cost?
Lock in a cheap one-way flight from $38 or cheap return flight from $136 from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU)?
October is the least expensive month to fly from PSA to BRU. Planning your trip for the off-season is often the key to finding better fares.
What is the cheapest airline that flies from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU)?
To find the cheapest airline that'll fly you from PSA to BRU, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU)?
Direct flights from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PSA to BRU?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU)?
To arrive at Brussels - National Airport (BRU) on schedule, opt for a flight that takes off from Galileo Galilei Airport (PSA) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Brussels from Galileo Galilei Airport (PSA)?
If you're traveling on a direct flight from Galileo Galilei Airport (PSA) to Brussels, Brussels South Charleroi Airport (CRL) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU) last-minute?
Waiting until just before your trip to book a flight from PSA to BRU often results in higher prices. While it's possible to find some last-minute discounts, they're not always guaranteed. Keep your travel plans flexible for a better chance of snagging a bargain.
Is it cheaper to book a PSA to BRU flight and hotel package?
You'll generally save money by securing a PSA to BRU flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After choosing your preferred accommodations and flights, you can add extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU)?
If you reserved your PSA to BRU flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

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*Available to One Key members.