$129 Cheap Flights from Des Moines (DSM) to Tampa (TPA)

View $129 flight on Tue, Sep 23, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Tampa Intl. Airport (TPA)

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Cheap Flights from Des Moines to Tampa (DSM-TPA)

Prices were available within the past 7 days and start at $129 for one-way flights and $223 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Sat, Oct 4 - Wed, Oct 8
DSM
Des Moines
TPA
Tampa
$223 Roundtrip, found 6 days ago
$223
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Sat, Oct 4 from Des Moines to Tampa, returning Wed, Oct 8, priced at $223 found 6 days ago
Southwest Airlines
Sat, Oct 4 - Sat, Oct 11
DSM
Des Moines
TPA
Tampa
$236 Roundtrip, found 5 days ago
$236
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sat, Oct 4 from Des Moines to Tampa, returning Sat, Oct 11, priced at $236 found 5 days ago
Frontier Airlines
Fri, Aug 29 - Wed, Sep 10
DSM
Des Moines
TPA
Tampa
$238 Roundtrip, found 6 days ago
$238
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Aug 29 from Des Moines to Tampa, returning Wed, Sep 10, priced at $238 found 6 days ago
Southwest Airlines
Sat, Oct 4 - Sat, Oct 11
DSM
Des Moines
TPA
Tampa
$241 Roundtrip, found 5 days ago
$241
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sat, Oct 4 from Des Moines to Tampa, returning Sat, Oct 11, priced at $241 found 5 days ago
Delta
Sat, Oct 25 - Tue, Oct 28
DSM
Des Moines
TPA
Tampa
$243 Roundtrip, found 5 days ago
$243
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Oct 25 from Des Moines to Tampa, returning Tue, Oct 28, priced at $243 found 5 days ago
Southwest Airlines
Tue, Sep 2 - Wed, Sep 3
DSM
Des Moines
TPA
Tampa
$247 Roundtrip, found 5 days ago
$247
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Sep 2 from Des Moines to Tampa, returning Wed, Sep 3, priced at $247 found 5 days ago
Southwest Airlines
Sat, Oct 25 - Tue, Oct 28
DSM
Des Moines
TPA
Tampa
$249 Roundtrip, found 5 days ago
$249
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sat, Oct 25 from Des Moines to Tampa, returning Tue, Oct 28, priced at $249 found 5 days ago
Southwest Airlines
Sat, Oct 25 - Tue, Oct 28
DSM
Des Moines
TPA
Tampa
$254 Roundtrip, found 5 days ago
$254
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sat, Oct 25 from Des Moines to Tampa, returning Tue, Oct 28, priced at $254 found 5 days ago
American Airlines
Tue, Dec 9 - Wed, Dec 10
DSM
Des Moines
TPA
Tampa
$257 Roundtrip, found 14 hours ago
$257
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Tue, Dec 9 from Des Moines to Tampa, returning Wed, Dec 10, priced at $257 found 14 hours ago
United
Tue, Sep 23 - Mon, Sep 29
DSM
Des Moines
TPA
Tampa
$267 Roundtrip, found 4 hours ago
$267
Roundtrip
found 4 hours ago
Select United flight, departing Tue, Sep 23 from Des Moines to Tampa, returning Mon, Sep 29, priced at $267 found 4 hours ago

Find the cheapest month to fly from Des Moines (DSM) to Tampa (TPA)

November is typically the cheapest month to fly

From $118 - $473 per traveler.

Graph displaying average flight prices per month

Alternative airports near Tampa

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tampa Intl. TPA. Cheapest option available. Average driving time to city center is 10 minutes. Flights from $355
TPA
Tampa Intl.
Cheapest
Average driving time to city center10 min
Flights from $355
Flights from Des Moines (DSM) to Tampa (TPA)
Origin airport
Des Moines Intl.
Destination airport
Tampa Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$222
Distance
1126 mi

Des Moines to Tampa Flights

The cheapest times to fly from Des Moines to Tampa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Tampa are during the month of October. You can find some of the cheapest flights from Des Moines to Tampa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Tampa

Sunday is one of the best days to book for cheap flights from Des Moines to Tampa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Tampa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Tampa in 2025. You can also book with separate airlines for your outbound and return journeys, from $129 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Tampa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Tampa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Tampa Intl. Airport (TPA) cost?
Secure a cheap one-way flight from $129 or cheap return flight from $223 from Des Moines Intl. Airport (DSM) to Tampa Intl. Airport (TPA) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Tampa Intl. Airport (TPA)?
The cheapest month to fly from DSM to TPA is October, when demand is low. Off-peak months are often when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Tampa Intl. Airport (TPA)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest DSM to TPA flight.
How many flights per day from Des Moines Intl. Airport (DSM) to Tampa Intl. Airport (TPA)?
You'll have to catch a flight with a layover when traveling from Des Moines Intl. Airport (DSM) to Tampa Intl. Airport (TPA). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from DSM to TPA?
Usually you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Tampa Intl. Airport (TPA)?
To reach Tampa Intl. Airport (TPA) on schedule, opt for a flight that leaves from Des Moines Intl. Airport (DSM) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Tampa from Des Moines Intl. Airport (DSM)?
If you're leaving on a direct flight from Des Moines Intl. Airport (DSM) to Tampa, you'll land at either Sarasota-Bradenton Intl. Airport (SRQ) or St. Petersburg-Clearwater Intl. Airport (PIE).
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Tampa Intl. Airport (TPA) last-minute?
Waiting until just before your trip to book a ticket from DSM to TPA generally means paying more. Although you may find some last-minute deals, there's no guarantee. Be flexible with your travel plans for a better chance of landing a bargain.
Is it cheaper to book a DSM to TPA flight and hotel package?
Compared with arranging flights and hotels separately, booking a DSM to TPA flight and hotel package with Expedia could result in significant savings. What's more, having everything in one easy place will take the stress out of planning your trip. Simply pick your flights and select from our wide range of stays, then personalize your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Tampa Intl. Airport (TPA)?
Generally, it's possible to reschedule or cancel your DSM to TPA flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.