$244 Cheap Flights from Greenville (GSP) to Santa Fe (SAF)

View $244 flight on Wed, Nov 5, 2025Opens in a new window

Popular airlines from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF)

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Cheap Flights from Greenville to Santa Fe (GSP-SAF)

Prices were available within the past 7 days and start at $244 for one-way flights and $264 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Nov 5 - Sat, Nov 8
GSP
Greenville
SAF
Santa Fe
$264 Roundtrip, found 17 hours ago
$264
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Wed, Nov 5 from Greenville to Santa Fe, returning Sat, Nov 8, priced at $264 found 17 hours ago
American Airlines
Sat, Nov 8 - Tue, Nov 11
GSP
Greenville
SAF
Santa Fe
$274 Roundtrip, found 1 day ago
$274
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Nov 8 from Greenville to Santa Fe, returning Tue, Nov 11, priced at $274 found 1 day ago
American Airlines
Wed, Oct 1 - Sat, Oct 4
GSP
Greenville
SAF
Santa Fe
$289 Roundtrip, found 14 hours ago
$289
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Oct 1 from Greenville to Santa Fe, returning Sat, Oct 4, priced at $289 found 14 hours ago
American Airlines
Wed, Nov 5 - Sat, Nov 8
GSP
Greenville
SAF
Santa Fe
$314 Roundtrip, found 17 hours ago
$314
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Wed, Nov 5 from Greenville to Santa Fe, returning Sat, Nov 8, priced at $314 found 17 hours ago
American Airlines
Fri, Dec 12 - Wed, Dec 17
GSP
Greenville
SAF
Santa Fe
$319 Roundtrip, found 4 days ago
$319
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Dec 12 from Greenville to Santa Fe, returning Wed, Dec 17, priced at $319 found 4 days ago
American Airlines
Sat, Nov 8 - Tue, Nov 11
GSP
Greenville
SAF
Santa Fe
$324 Roundtrip, found 1 day ago
$324
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Nov 8 from Greenville to Santa Fe, returning Tue, Nov 11, priced at $324 found 1 day ago
American Airlines
Sat, Nov 1 - Tue, Nov 18
GSP
Greenville
SAF
Santa Fe
$344 Roundtrip, found 10 hours ago
$344
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Sat, Nov 1 from Greenville to Santa Fe, returning Tue, Nov 18, priced at $344 found 10 hours ago
American Airlines
Tue, Dec 16 - Thu, Dec 25
GSP
Greenville
SAF
Santa Fe
$354 Roundtrip, found 1 hour ago
$354
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Tue, Dec 16 from Greenville to Santa Fe, returning Thu, Dec 25, priced at $354 found 1 hour ago
American Airlines
Thu, Oct 30 - Mon, Nov 17
GSP
Greenville
SAF
Santa Fe
$359 Roundtrip, found 10 hours ago
$359
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Thu, Oct 30 from Greenville to Santa Fe, returning Mon, Nov 17, priced at $359 found 10 hours ago
United
Fri, Oct 31 - Tue, Nov 18
GSP
Greenville
SAF
Santa Fe
$369 Roundtrip, found 10 hours ago
$369
Roundtrip
found 10 hours ago
Select United flight, departing Fri, Oct 31 from Greenville to Santa Fe, returning Tue, Nov 18, priced at $369 found 10 hours ago

Alternative airports near Santa Fe

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Santa Fe Municipal SAF. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $379
SAF
Santa Fe Municipal
CheapestClosest
Average driving time to city center17 min
Flights from $379
Flights from Greenville (GSP) to Santa Fe (SAF)
Origin airport
Greenville-Spartanburg Intl.
Destination airport
Santa Fe Municipal
Airlines serving
American Airlines, United
Roundtrip price
$264
Distance
1344 mi

Greenville to Santa Fe Flights

The cheapest times to fly from Greenville to Santa Fe

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Greenville to Santa Fe are during the month of November. You can find some of the cheapest flights from Greenville to Santa Fe with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Greenville to Santa Fe

Sunday is one of the best days to book for cheap flights from Greenville to Santa Fe: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Greenville to Santa Fe

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Greenville to Santa Fe in 2025. You can also book with separate airlines for your outbound and return journeys, from $244 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Greenville to Santa Fe flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Greenville to Santa Fe airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF) cost?
Snag a cheap one-way flight from $244 or cheap return flight from $264 from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF)?
November is the cheapest month to fly from GSP to SAF. Planning your trip for the off-season is often the key to finding better deals on flights.
What is the cheapest airline that flies from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF)?
To find the cheapest airline flying from GSP to SAF, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF)?
You'll have to hop on a flight with a layover if you're traveling from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from GSP to SAF?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on a number of factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF)?
Book a flight from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF) that takes off before 3 PM to reduce the risk of delays and cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF) last-minute?
Last-minute bookings from GSP to SAF are usually more expensive. For the best prices, start looking for flights as soon as possible. That said, if you're flexible with your travel dates, you may find a cheap ticket right before your journey.
Is it cheaper to book a GSP to SAF flight and hotel package?
You'll generally save money by securing a GSP to SAF flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your preferred flights and accommodations, you can add extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Greenville-Spartanburg Intl. Airport (GSP) to Santa Fe Municipal Airport (SAF)?
Typically, you can cancel or modify your GSP to SAF flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you want more information, head to our Customer Service portal.

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*Available to One Key members.