$121 Cheap Flights from Charleston (CHS) to Santo Domingo (SDQ)

View $121 flight on Fri, Dec 5, 2025Opens in a new window

Popular airlines from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)

Cheap Flights from Charleston to Santo Domingo (CHS-SDQ)

Prices were available within the past 7 days and start at $121 for one-way flights and $277 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Fri, Nov 14 - Thu, Nov 20
CHS
Charleston
SDQ
Santo Domingo
$277 Roundtrip, found 5 days ago
$277
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Fri, Nov 14 from Charleston to Santo Domingo, returning Thu, Nov 20, priced at $277 found 5 days ago
American Airlines
Fri, Nov 14 - Fri, Nov 21
CHS
Charleston
SDQ
Santo Domingo
$300 Roundtrip, found 3 days ago
$300
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Nov 14 from Charleston to Santo Domingo, returning Fri, Nov 21, priced at $300 found 3 days ago
Spirit Airlines
Mon, Dec 1 - Fri, Dec 5
CHS
Charleston
SDQ
Santo Domingo
$302 Roundtrip, found 13 hours ago
$302
Roundtrip
found 13 hours ago
Select Spirit Airlines flight, departing Mon, Dec 1 from Charleston to Santo Domingo, returning Fri, Dec 5, priced at $302 found 13 hours ago
Spirit Airlines
Tue, Dec 2 - Tue, Dec 9
CHS
Charleston
SDQ
Santo Domingo
$304 Roundtrip, found 6 days ago
$304
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Tue, Dec 2 from Charleston to Santo Domingo, returning Tue, Dec 9, priced at $304 found 6 days ago
American Airlines
Fri, Nov 14 - Fri, Nov 21
CHS
Charleston
SDQ
Santo Domingo
$312 Roundtrip, found 3 days ago
$312
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Nov 14 from Charleston to Santo Domingo, returning Fri, Nov 21, priced at $312 found 3 days ago
Delta
Thu, Jan 1 - Mon, Feb 2
CHS
Charleston
SDQ
Santo Domingo
$318 Roundtrip, found 5 hours ago
$318
Roundtrip
found 5 hours ago
Select Delta flight, departing Thu, Jan 1 from Charleston to Santo Domingo, returning Mon, Feb 2, priced at $318 found 5 hours ago
United
Mon, Nov 24 - Sat, Dec 6
CHS
Charleston
SDQ
Santo Domingo
$318 Roundtrip, found 1 day ago
$318
Roundtrip
found 1 day ago
Select United flight, departing Mon, Nov 24 from Charleston to Santo Domingo, returning Sat, Dec 6, priced at $318 found 1 day ago
American Airlines
Wed, Nov 26 - Wed, Dec 3
CHS
Charleston
SDQ
Santo Domingo
$318 Roundtrip, just found
$318
Roundtrip
just found
Select American Airlines flight, departing Wed, Nov 26 from Charleston to Santo Domingo, returning Wed, Dec 3, priced at $318 just found
Spirit Airlines
Fri, Nov 28 - Sun, Dec 7
CHS
Charleston
SDQ
Santo Domingo
$319 Roundtrip, just found
$319
Roundtrip
just found
Select Spirit Airlines flight, departing Fri, Nov 28 from Charleston to Santo Domingo, returning Sun, Dec 7, priced at $319 just found
JetBlue Airways
Mon, Nov 24 - Thu, Dec 4
CHS
Charleston
SDQ
Santo Domingo
$329 Roundtrip, found 7 hours ago
$329
Roundtrip
found 7 hours ago
Select JetBlue Airways flight, departing Mon, Nov 24 from Charleston to Santo Domingo, returning Thu, Dec 4, priced at $329 found 7 hours ago

Find the cheapest month to fly from Charleston (CHS) to Santo Domingo (SDQ)

September is typically the cheapest month to fly

From $256 - $476 per traveler.

Alternative airports near Santo Domingo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $521
SDQ
Las Americas Intl.
Cheapest
Average driving time to city center22 min
Flights from $521

Frequently asked questions

How much does a flight from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ) cost?
Lock in a cheap one-way flight from $121 or cheap return flight from $277 from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)?
November is the most affordable month to fly from CHS to SDQ. Traveling outside of peak seasons is often the key to scoring lower fares.
What is the cheapest airline that flies from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)?
To find the cheapest airline flying from CHS to SDQ, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)?
Nonstop flights from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CHS to SDQ?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)?
To avoid potential delays on the Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ) route, aim to fly before 3 PM. Later flights have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ) last-minute?
Booking your flight from CHS to SDQ right before your trip is generally more expensive. However, if there's some wiggle room with your travel times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a CHS to SDQ flight and hotel package?
Compared with arranging hotels and flights separately, booking a CHS to SDQ flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place takes the hassle out of travel planning. Just secure your flights and select from our wide range of stays, then tailor your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)?
You can usually cancel or reschedule your CHS to SDQ flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Charleston Intl.
Destination airport
Las Americas Intl.
Airlines serving
American Airlines, Copa, Delta, JetBlue Airways, Spirit Airlines, United
Roundtrip price
$276
Distance
1187 mi

Book with confidence

Charleston to Santo Domingo Flights

The cheapest times to fly from Charleston to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to Santo Domingo are during the month of November. You can find some of the cheapest flights from Charleston to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charleston to Santo Domingo

Sunday is one of the best days to book for cheap flights from Charleston to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charleston to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $121 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charleston to Santo Domingo Flights

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*Available to One Key members.