$484 Cheap Flights from Denver (DEN) to Santiago Island (RAI)

View $484 flight on Wed, Oct 22, 2025Opens in a new window

Popular airlines from Denver Intl. Airport (DEN) to Santiago Island (RAI-Praia Intl.)

Cheap Flights from Denver to Santiago Island (DEN-RAI)

Prices were available within the past 7 days and start at $484 for one-way flights and $1,319 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Wed, Nov 26 - Mon, Dec 1
DEN
Denver
RAI
Santiago
$1,319 Roundtrip, found 1 day ago
$1,319
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Wed, Nov 26 from Denver to Santiago, returning Mon, Dec 1, priced at $1,319 found 1 day ago
JetBlue Airways
Wed, Nov 26 - Mon, Dec 1
DEN
Denver
RAI
Santiago
$1,327 Roundtrip, found 1 day ago
$1,327
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Wed, Nov 26 from Denver to Santiago, returning Mon, Dec 1, priced at $1,327 found 1 day ago
JetBlue Airways
Fri, Mar 20 - Sat, Mar 28
DEN
Denver
RAI
Santiago
$1,409 Roundtrip, found 5 days ago
$1,409
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Fri, Mar 20 from Denver to Santiago, returning Sat, Mar 28, priced at $1,409 found 5 days ago
JetBlue Airways
Mon, Jun 1 - Mon, Jun 15
DEN
Denver
RAI
Santiago
$1,442 Roundtrip, found 2 days ago
$1,442
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Mon, Jun 1 from Denver to Santiago, returning Mon, Jun 15, priced at $1,442 found 2 days ago
Brussels Airlines
Wed, Nov 12 - Wed, Nov 19
DEN
Denver
RAI
Santiago
$1,482 Roundtrip, found 1 day ago
$1,482
Roundtrip
found 1 day ago
Select Brussels Airlines flight, departing Wed, Nov 12 from Denver to Santiago, returning Wed, Nov 19, priced at $1,482 found 1 day ago
Air Canada
Wed, Nov 12 - Wed, Nov 19
DEN
Denver
RAI
Santiago
$1,484 Roundtrip, found 1 day ago
$1,484
Roundtrip
found 1 day ago
Select Air Canada flight, departing Wed, Nov 12 from Denver to Santiago, returning Wed, Nov 19, priced at $1,484 found 1 day ago
Lufthansa
Wed, Nov 12 - Wed, Nov 19
DEN
Denver
RAI
Santiago
$1,488 Roundtrip, found 1 day ago
$1,488
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Wed, Nov 12 from Denver to Santiago, returning Wed, Nov 19, priced at $1,488 found 1 day ago
Air Canada
Wed, Nov 12 - Wed, Nov 19
DEN
Denver
RAI
Santiago
$1,490 Roundtrip, found 1 day ago
$1,490
Roundtrip
found 1 day ago
Select Air Canada flight, departing Wed, Nov 12 from Denver to Santiago, returning Wed, Nov 19, priced at $1,490 found 1 day ago
Air Canada
Wed, Nov 12 - Wed, Nov 19
DEN
Denver
RAI
Santiago
$1,491 Roundtrip, found 1 day ago
$1,491
Roundtrip
found 1 day ago
Select Air Canada flight, departing Wed, Nov 12 from Denver to Santiago, returning Wed, Nov 19, priced at $1,491 found 1 day ago
Swiss International Air Lines
Wed, Nov 26 - Mon, Dec 1
DEN
Denver
RAI
Santiago
$1,502 Roundtrip, found 1 day ago
$1,502
Roundtrip
found 1 day ago
Select Swiss International Air Lines flight, departing Wed, Nov 26 from Denver to Santiago, returning Mon, Dec 1, priced at $1,502 found 1 day ago
Flights from Denver (DEN) to Santiago Island (RAI)
Origin airport
Denver Intl.
Destination airport
Praia Intl.
Roundtrip price
$1,319
Distance
5099 mi

Denver to Santiago Island Flights

The cheapest times to fly from Denver to Santiago Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Denver to Santiago Island are during the month of November. You can find some of the cheapest flights from Denver to Santiago Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Denver to Santiago Island

Sunday is one of the best days to book for cheap flights from Denver to Santiago Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Denver to Santiago Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Denver to Santiago Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $484 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Denver to Santiago Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Denver to Santiago Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI) cost?
Lock in a cheap one-way flight from $484 or cheap return flight from $1,319 from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
Planning your trip for November is a great way to save, as it's the cheapest month for flights between DEN and RAI. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
To find the cheapest airline flying from DEN to RAI, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
Direct flights from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DEN to RAI?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
To land at Praia Intl. Airport (RAI) on schedule, choose a flight that leaves from Denver Intl. Airport (DEN) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI) last-minute?
Booking your plane ticket from DEN to RAI just before your trip is usually more expensive. However, if you're flexible with your itinerary, you could bag a cheap last-minute fare.
Is it cheaper to book a DEN to RAI flight and hotel package?
You'll typically save money by securing a DEN to RAI flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've chosen your preferred accommodations and flights, you can add extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
Typically, you can cancel or modify your DEN to RAI flight. However, there may be additional charges, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like more details, visit our Customer Service portal.

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*Available to One Key members.