$484 Cheap Flights from Denver (DEN) to Santiago Island (RAI)

View $484 flight on Wed, Oct 22, 2025Opens in a new window

Popular airlines from Denver Intl. Airport (DEN) to Santiago Island (RAI-Praia Intl.)

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Cheap Flights from Denver to Santiago Island (DEN-RAI)

Prices were available within the past 7 days and start at $484 for one-way flights and $1,268 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Swiss International Air Lines
Tue, Jan 6 - Thu, Jan 15
DEN
Denver
RAI
Santiago
$1,268 Roundtrip, found 1 hour ago
$1,268
Roundtrip
found 1 hour ago
Select Swiss International Air Lines flight, departing Tue, Jan 6 from Denver to Santiago, returning Thu, Jan 15, priced at $1,268 found 1 hour ago
Swiss International Air Lines
Tue, Jan 6 - Thu, Jan 15
DEN
Denver
RAI
Santiago
$1,277 Roundtrip, found 1 hour ago
$1,277
Roundtrip
found 1 hour ago
Select Swiss International Air Lines flight, departing Tue, Jan 6 from Denver to Santiago, returning Thu, Jan 15, priced at $1,277 found 1 hour ago
Swiss International Air Lines
Tue, Jan 6 - Thu, Jan 15
DEN
Denver
RAI
Santiago
$1,283 Roundtrip, found 1 hour ago
$1,283
Roundtrip
found 1 hour ago
Select Swiss International Air Lines flight, departing Tue, Jan 6 from Denver to Santiago, returning Thu, Jan 15, priced at $1,283 found 1 hour ago
Swiss International Air Lines
Tue, Jan 6 - Thu, Jan 15
DEN
Denver
RAI
Santiago
$1,300 Roundtrip, found 1 hour ago
$1,300
Roundtrip
found 1 hour ago
Select Swiss International Air Lines flight, departing Tue, Jan 6 from Denver to Santiago, returning Thu, Jan 15, priced at $1,300 found 1 hour ago
JetBlue Airways
Wed, Nov 26 - Mon, Dec 1
DEN
Denver
RAI
Santiago
$1,319 Roundtrip, found 2 days ago
$1,319
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Wed, Nov 26 from Denver to Santiago, returning Mon, Dec 1, priced at $1,319 found 2 days ago
JetBlue Airways
Wed, Nov 26 - Mon, Dec 1
DEN
Denver
RAI
Santiago
$1,327 Roundtrip, found 2 days ago
$1,327
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Wed, Nov 26 from Denver to Santiago, returning Mon, Dec 1, priced at $1,327 found 2 days ago
JetBlue Airways
Tue, Jan 6 - Thu, Jan 15
DEN
Denver
RAI
Santiago
$1,327 Roundtrip, found 1 hour ago
$1,327
Roundtrip
found 1 hour ago
Select JetBlue Airways flight, departing Tue, Jan 6 from Denver to Santiago, returning Thu, Jan 15, priced at $1,327 found 1 hour ago
Air Canada
Tue, Jan 6 - Thu, Jan 15
DEN
Denver
RAI
Santiago
$1,359 Roundtrip, found 1 hour ago
$1,359
Roundtrip
found 1 hour ago
Select Air Canada flight, departing Tue, Jan 6 from Denver to Santiago, returning Thu, Jan 15, priced at $1,359 found 1 hour ago
Lufthansa
Tue, Jan 6 - Thu, Jan 15
DEN
Denver
RAI
Santiago
$1,394 Roundtrip, found 1 hour ago
$1,394
Roundtrip
found 1 hour ago
Select Lufthansa flight, departing Tue, Jan 6 from Denver to Santiago, returning Thu, Jan 15, priced at $1,394 found 1 hour ago
TAP Portugal
Wed, Nov 12 - Wed, Nov 19
DEN
Denver
RAI
Santiago
$1,870 Roundtrip, found 1 day ago
$1,870
Roundtrip
found 1 day ago
Select TAP Portugal flight, departing Wed, Nov 12 from Denver to Santiago, returning Wed, Nov 19, priced at $1,870 found 1 day ago

Frequently asked questions

How much does a flight from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI) cost?
Lock in a cheap one-way flight from $484 or cheap return flight from $1,268 from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
Planning your trip for January is a great way to save, as it's the cheapest month for flights between DEN and RAI. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
To find the cheapest airline flying from DEN to RAI, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
Direct flights from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DEN to RAI?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
To land at Praia Intl. Airport (RAI) on schedule, choose a flight that leaves from Denver Intl. Airport (DEN) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI) last-minute?
Booking your plane ticket from DEN to RAI just before your trip is usually more expensive. However, if you're flexible with your itinerary, you could bag a cheap last-minute fare.
Is it cheaper to book a DEN to RAI flight and hotel package?
You'll typically save money by securing a DEN to RAI flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've chosen your preferred accommodations and flights, you can add extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Denver Intl. Airport (DEN) to Praia Intl. Airport (RAI)?
Typically, you can cancel or modify your DEN to RAI flight. However, there may be additional charges, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like more details, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Denver Intl.
Destination airport
Praia Intl.
Roundtrip price
$1,267
Distance
5099 mi

Book with confidence

Book with confidence

Denver to Santiago Island Flights

The cheapest times to fly from Denver to Santiago Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Denver to Santiago Island are during the month of January. You can find some of the cheapest flights from Denver to Santiago Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Denver to Santiago Island

Sunday is one of the best days to book for cheap flights from Denver to Santiago Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Denver to Santiago Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Denver to Santiago Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $484 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Denver to Santiago Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Denver to Santiago Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Denver to Santiago Island Flights
*Available to One Key members.