$603 Cheap Flights from Detroit (DTW) to Santander (SDR)

View $603 flight on Sat, Oct 4, 2025Opens in a new window

Popular airlines from Detroit Metropolitan Wayne County Airport (DTW) to Santander (SDR)

Cheap Flights from Detroit to Santander (DTW-SDR)

Prices were available within the past 7 days and start at $603 for one-way flights and $743 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Sat, Feb 21 - Sat, Feb 28
DTW
Detroit
SDR
Santander
$743 Roundtrip, found 1 day ago
$743
Roundtrip
found 1 day ago
Select British Airways flight, departing Sat, Feb 21 from Detroit to Santander, returning Sat, Feb 28, priced at $743 found 1 day ago
Iberia
Sat, Nov 8 - Sat, Nov 15
DTW
Detroit
SDR
Santander
$743 Roundtrip, found 4 days ago
$743
Roundtrip
found 4 days ago
Select Iberia flight, departing Sat, Nov 8 from Detroit to Santander, returning Sat, Nov 15, priced at $743 found 4 days ago
Iberia
Sat, Nov 8 - Sat, Nov 15
DTW
Detroit
SDR
Santander
$751 Roundtrip, found 4 days ago
$751
Roundtrip
found 4 days ago
Select Iberia flight, departing Sat, Nov 8 from Detroit to Santander, returning Sat, Nov 15, priced at $751 found 4 days ago
British Airways
Sat, Feb 21 - Sat, Feb 28
DTW
Detroit
SDR
Santander
$777 Roundtrip, found 1 day ago
$777
Roundtrip
found 1 day ago
Select British Airways flight, departing Sat, Feb 21 from Detroit to Santander, returning Sat, Feb 28, priced at $777 found 1 day ago
British Airways
Sat, Feb 21 - Sat, Feb 28
DTW
Detroit
SDR
Santander
$779 Roundtrip, found 1 day ago
$779
Roundtrip
found 1 day ago
Select British Airways flight, departing Sat, Feb 21 from Detroit to Santander, returning Sat, Feb 28, priced at $779 found 1 day ago
British Airways
Sat, Feb 21 - Sat, Feb 28
DTW
Detroit
SDR
Santander
$786 Roundtrip, found 1 day ago
$786
Roundtrip
found 1 day ago
Select British Airways flight, departing Sat, Feb 21 from Detroit to Santander, returning Sat, Feb 28, priced at $786 found 1 day ago
British Airways
Sat, Feb 21 - Sat, Feb 28
DTW
Detroit
SDR
Santander
$787 Roundtrip, found 1 day ago
$787
Roundtrip
found 1 day ago
Select British Airways flight, departing Sat, Feb 21 from Detroit to Santander, returning Sat, Feb 28, priced at $787 found 1 day ago
Iberia
Sat, Nov 8 - Sat, Nov 15
DTW
Detroit
SDR
Santander
$791 Roundtrip, found 4 days ago
$791
Roundtrip
found 4 days ago
Select Iberia flight, departing Sat, Nov 8 from Detroit to Santander, returning Sat, Nov 15, priced at $791 found 4 days ago
British Airways
Sat, Feb 21 - Sat, Feb 28
DTW
Detroit
SDR
Santander
$796 Roundtrip, found 1 day ago
$796
Roundtrip
found 1 day ago
Select British Airways flight, departing Sat, Feb 21 from Detroit to Santander, returning Sat, Feb 28, priced at $796 found 1 day ago
Iberia
Sat, Nov 8 - Sat, Nov 15
DTW
Detroit
SDR
Santander
$800 Roundtrip, found 4 days ago
$800
Roundtrip
found 4 days ago
Select Iberia flight, departing Sat, Nov 8 from Detroit to Santander, returning Sat, Nov 15, priced at $800 found 4 days ago

Frequently asked questions

How much does a flight from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR) cost?
Snag a cheap one-way flight from $603 or cheap return flight from $743 from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR)?
February is the cheapest month to fly from DTW to SDR. Traveling during quieter months is often the key to finding a great deal.
What is the cheapest airline that flies from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll fly you from DTW to SDR. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR)?
You'll have to take a flight with a layover when traveling from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from DTW to SDR?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change depending on a number of factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR)?
Choose a flight from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR) that takes off before 3 PM to reduce the risk of delays and cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR) last-minute?
Booking your flight from DTW to SDR just before your journey is usually more expensive. But if there's some wiggle room with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a DTW to SDR flight and hotel package?
You'll generally save money by booking a DTW to SDR flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've chosen your preferred accommodations and flights, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Detroit Metropolitan Wayne County Airport (DTW) to Santander Airport (SDR)?
Generally, it's possible to cancel or reschedule your DTW to SDR flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
Detroit Metropolitan Wayne County
Destination airport
Santander
Airlines serving
Iberia
Roundtrip price
$742
Distance
3866 mi

Book with confidence

Book with confidence

Detroit to Santander Flights

The cheapest times to fly from Detroit to Santander

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Detroit to Santander are during the month of February. You can find some of the cheapest flights from Detroit to Santander with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Detroit to Santander

Sunday is one of the best days to book for cheap flights from Detroit to Santander: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Detroit to Santander

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Detroit to Santander in 2025. You can also book with separate airlines for your outbound and return journeys, from $603 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Detroit to Santander flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Detroit to Santander airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Detroit to Santander Flights

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*Available to One Key members.