$343 Cheap Flights from Panama City (ECP) to St. John's (ANU)

View $343 flight on Wed, Jan 28, 2026Opens in a new window

Popular airlines from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU)

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Cheap Flights from Panama City to St. John's (ECP-ANU)

Prices were available within the past 7 days and start at $343 for one-way flights and $585 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$585 Roundtrip, found 7 hours ago
$585
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $585 found 7 hours ago
American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$593 Roundtrip, found 7 hours ago
$593
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $593 found 7 hours ago
American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$593 Roundtrip, found 7 hours ago
$593
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $593 found 7 hours ago
American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$601 Roundtrip, found 7 hours ago
$601
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $601 found 7 hours ago
American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$602 Roundtrip, found 7 hours ago
$602
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $602 found 7 hours ago
American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$674 Roundtrip, found 7 hours ago
$674
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $674 found 7 hours ago
American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$676 Roundtrip, found 7 hours ago
$676
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $676 found 7 hours ago
American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$676 Roundtrip, found 7 hours ago
$676
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $676 found 7 hours ago
American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$683 Roundtrip, found 7 hours ago
$683
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $683 found 7 hours ago
American Airlines
Wed, Jan 28 - Wed, Feb 4
ECP
Panama City
ANU
Antigua
$684 Roundtrip, found 7 hours ago
$684
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Panama City to Antigua, returning Wed, Feb 4, priced at $684 found 7 hours ago
Flights from Panama City (ECP) to St. John's (ANU)
Origin airport
Northwest Florida Beaches Intl.
Destination airport
V.C. Bird Intl.
Roundtrip price
$584
Distance
1765 mi

Panama City to St. John's Flights

The cheapest times to fly from Panama City to St. John's

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to St. John's are during the month of January. You can find some of the cheapest flights from Panama City to St. John's with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to St. John's

Sunday is one of the best days to book for cheap flights from Panama City to St. John's: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to St. John's

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to St. John's in 2025. You can also book with separate airlines for your outbound and return journeys, from $343 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to St. John's flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to St. John's airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU) cost?
Snag a cheap one-way flight from $343 or cheap return flight from $585 from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU)?
Planning your getaway for January is a great way to save, as it's the cheapest month for flights between ECP and ANU. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest ECP to ANU flight.
How many flights per day from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU)?
You'll need to take a flight with a layover when traveling from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from ECP to ANU?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a range of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU)?
Book a flight from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU) last-minute?
Holding off until just before your trip to book your flight from ECP to ANU often results in higher prices. Although you may find some last-minute discounts, they're not always guaranteed. Keep your travel schedule open for a better chance of getting a bargain.
Is it cheaper to book an ECP to ANU flight and hotel package?
You can save money by securing an ECP to ANU flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. Once you've chosen your preferred accommodations and flights, consider other add-ons like activities, car rentals and tours.
Can I cancel or change the date of my flight from Northwest Florida Beaches Intl. Airport (ECP) to V.C. Bird Intl. Airport (ANU)?
If you booked your ECP to ANU flight in the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for further details.

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*Available to One Key members.