$108 Cheap Flights from Panama City (ECP) to Greenville (GSP)

View $108 flight on Tue, Oct 28, 2025Opens in a new window

Popular airlines from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP)

Cheap Flights from Panama City to Greenville (ECP-GSP)

Prices were available within the past 7 days and start at $108 for one-way flights and $215 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Dec 2 - Tue, Dec 9
ECP
Panama City
GSP
Greenville
$215 Roundtrip, found 2 days ago
$215
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Dec 2 from Panama City to Greenville, returning Tue, Dec 9, priced at $215 found 2 days ago
Delta
Tue, Dec 2 - Mon, Dec 8
ECP
Panama City
GSP
Greenville
$229 Roundtrip, found 2 days ago
$229
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Dec 2 from Panama City to Greenville, returning Mon, Dec 8, priced at $229 found 2 days ago
Delta
Sat, Dec 6 - Tue, Dec 9
ECP
Panama City
GSP
Greenville
$243 Roundtrip, found 2 days ago
$243
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Dec 6 from Panama City to Greenville, returning Tue, Dec 9, priced at $243 found 2 days ago
Southwest Airlines
Sat, Nov 8 - Mon, Nov 10
ECP
Panama City
GSP
Greenville
$257 Roundtrip, found 4 days ago
$257
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Sat, Nov 8 from Panama City to Greenville, returning Mon, Nov 10, priced at $257 found 4 days ago
Southwest Airlines
Tue, Oct 28 - Thu, Oct 30
ECP
Panama City
GSP
Greenville
$258 Roundtrip, found 6 days ago
$258
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Oct 28 from Panama City to Greenville, returning Thu, Oct 30, priced at $258 found 6 days ago
American Airlines
Tue, Oct 28 - Thu, Oct 30
ECP
Panama City
GSP
Greenville
$260 Roundtrip, found 6 days ago
$260
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Oct 28 from Panama City to Greenville, returning Thu, Oct 30, priced at $260 found 6 days ago
Southwest Airlines
Tue, Oct 28 - Thu, Oct 30
ECP
Panama City
GSP
Greenville
$264 Roundtrip, found 6 days ago
$264
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Oct 28 from Panama City to Greenville, returning Thu, Oct 30, priced at $264 found 6 days ago
Southwest Airlines
Tue, Oct 28 - Thu, Oct 30
ECP
Panama City
GSP
Greenville
$267 Roundtrip, found 6 days ago
$267
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Oct 28 from Panama City to Greenville, returning Thu, Oct 30, priced at $267 found 6 days ago
Delta
Tue, Oct 28 - Thu, Oct 30
ECP
Panama City
GSP
Greenville
$269 Roundtrip, found 6 days ago
$269
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Oct 28 from Panama City to Greenville, returning Thu, Oct 30, priced at $269 found 6 days ago
United
Mon, Nov 24 - Thu, Nov 27
ECP
Panama City
GSP
Greenville
$751 Roundtrip, found 12 hours ago
$751
Roundtrip
found 12 hours ago
Select United flight, departing Mon, Nov 24 from Panama City to Greenville, returning Thu, Nov 27, priced at $751 found 12 hours ago

Find the cheapest month to fly from Panama City (ECP) to Greenville (GSP)

September is typically the cheapest month to fly

From $196 - $606 per traveler.

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $389
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $389
Flights from Panama City (ECP) to Greenville (GSP)
Origin airport
Northwest Florida Beaches Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$214
Distance
376 mi

Panama City to Greenville Flights

The cheapest times to fly from Panama City to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Greenville are during the month of December. You can find some of the cheapest flights from Panama City to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Greenville

Sunday is one of the best days to book for cheap flights from Panama City to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $108 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Get a cheap one-way flight from $108 or cheap return flight from $215 from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP)?
Planning your getaway for December can help you save, as it's the cheapest month for flights between ECP and GSP. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP)?
To find the cheapest airline flying from ECP to GSP, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP)?
You'll have to hop on a flight with a layover when traveling from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from ECP to GSP?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP)?
Select a flight from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP) that takes off before 3 PM to reduce the likelihood of delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Last-minute bookings from ECP to GSP are generally more expensive. To secure the best prices, start looking for flights as early as possible. That said, if you're flexible with your travel plans, you may find a cheap ticket right before your trip.
Is it cheaper to book an ECP to GSP flight and hotel package?
You can save money by booking an ECP to GSP flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've chosen your ideal accommodations and flights, you can add extras such as activities, tours and car rentals.
Can I cancel or change the date of my flight from Northwest Florida Beaches Intl. Airport (ECP) to Greenville-Spartanburg Intl. Airport (GSP)?
You can usually cancel or reschedule your ECP to GSP flight. However, for bookings made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.