$357 Cheap Flights from Sioux Falls (FSD) to Brussels (BRU)

View $357 flight on Wed, Jan 13, 2027Opens in a new window

Popular airlines from Sioux Falls Regional Airport (FSD) to Brussels Airport (BRU)

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Cheap Flights from Sioux Falls to Brussels (FSD-BRU)

Prices were available within the past 7 days and start at $357 for one-way flights and $806 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Jan 13 - Wed, Jan 20
FSD
Sioux Falls
BRU
Brussels
$806 Roundtrip, found 5 days ago
$806
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jan 13 from Sioux Falls to Brussels, returning Wed, Jan 20, priced at $806 found 5 days ago
American Airlines
Wed, Jan 13 - Wed, Jan 20
FSD
Sioux Falls
BRU
Brussels
$808 Roundtrip, found 5 days ago
$808
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jan 13 from Sioux Falls to Brussels, returning Wed, Jan 20, priced at $808 found 5 days ago
American Airlines
Wed, Jan 13 - Wed, Jan 20
FSD
Sioux Falls
BRU
Brussels
$814 Roundtrip, found 5 days ago
$814
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jan 13 from Sioux Falls to Brussels, returning Wed, Jan 20, priced at $814 found 5 days ago
Lufthansa
Wed, Jan 13 - Wed, Jan 20
FSD
Sioux Falls
BRU
Brussels
$825 Roundtrip, found 5 days ago
$825
Roundtrip
found 5 days ago
Select Lufthansa flight, departing Wed, Jan 13 from Sioux Falls to Brussels, returning Wed, Jan 20, priced at $825 found 5 days ago
United
Wed, Jan 13 - Wed, Jan 20
FSD
Sioux Falls
BRU
Brussels
$825 Roundtrip, found 5 days ago
$825
Roundtrip
found 5 days ago
Select United flight, departing Wed, Jan 13 from Sioux Falls to Brussels, returning Wed, Jan 20, priced at $825 found 5 days ago
United
Wed, Jan 13 - Wed, Jan 20
FSD
Sioux Falls
BRU
Brussels
$828 Roundtrip, found 5 days ago
$828
Roundtrip
found 5 days ago
Select United flight, departing Wed, Jan 13 from Sioux Falls to Brussels, returning Wed, Jan 20, priced at $828 found 5 days ago
United
Wed, Jan 13 - Wed, Jan 20
FSD
Sioux Falls
BRU
Brussels
$829 Roundtrip, found 5 days ago
$829
Roundtrip
found 5 days ago
Select United flight, departing Wed, Jan 13 from Sioux Falls to Brussels, returning Wed, Jan 20, priced at $829 found 5 days ago
United
Wed, Jan 13 - Wed, Jan 20
FSD
Sioux Falls
BRU
Brussels
$831 Roundtrip, found 5 days ago
$831
Roundtrip
found 5 days ago
Select United flight, departing Wed, Jan 13 from Sioux Falls to Brussels, returning Wed, Jan 20, priced at $831 found 5 days ago
Delta
Wed, Jan 13 - Wed, Jan 20
FSD
Sioux Falls
BRU
Brussels
$842 Roundtrip, found 5 days ago
$842
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Jan 13 from Sioux Falls to Brussels, returning Wed, Jan 20, priced at $842 found 5 days ago
Iberia
Wed, Jul 1 - Wed, Jul 8
FSD
Sioux Falls
BRU
Brussels
$1,536 Roundtrip, just found
$1,536
Roundtrip
just found
Select Iberia flight, departing Wed, Jul 1 from Sioux Falls to Brussels, returning Wed, Jul 8, priced at $1,536 just found

Frequently asked questions

How much does a flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) cost?
You can find cheap one-way flights from $357 and cheap return flights from $806 Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) with Expedia. Return flights often range between $698 and $3108. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
The cheapest month to fly from FSD to BRU is January when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
Enter FSD to BRU and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
Virgin Atlantic is one of the cheapest airlines offering connecting flights from Sioux Falls Regional (FSD) to Brussels - National (BRU), with round-trip tickets starting from around $805 with a layover in Minneapolis - St. Paul Intl. (MSP). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
To find a cheap flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
The earliest flight from Sioux Falls Regional Airport (FSD) to Brussels - National Airport (BRU) typically departs at around 5:00 AM, with options from Delta and KLM. An early departure allows you to maximize your time in Brussels. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
You'll usually find the most flights from Sioux Falls Regional (FSD) to Brussels - National (BRU) on a Saturday, with around 26 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include United, Delta, and American Airlines.
What are the most popular departure times for flights from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
The most popular departure times for flights from Sioux Falls, SD (FSD) to Brussels (BRU) are usually between 12pm and 3pm. This time slot captures around 46% of total traffic. Major airlines like United Airlines, Delta Air Lines, and American Airlines offer flights during this window. This timing is favored because it allows travelers to enjoy a full morning before their journey.
How long does it take to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
Flying from FSD to BRU with a connection usually takes about 10 hours 50 minutes, traveling roughly 4,388 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
Business class seats are offered on the FSD to BRU route with United Airlines and Delta Air Lines.
How do I earn miles on a Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) flight with Expedia?
It's easy to earn miles on a Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Brussels from Sioux Falls Regional (FSD)?
If you're planning to travel to Brussels from Sioux Falls Regional (FSD), you can fly into Brussels - National (BRU) Some flights may connect through major hubs like O'Hare Intl. (ORD), Minneapolis - St. Paul Intl. (MSP), Denver Intl. (DEN) before reaching Brussels. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) at the last minute?
Typically, booking a last minute flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) flight and hotel package?
Securing a Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) Brussels Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National)?
If you booked your Sioux Falls, SD (FSD-Sioux Falls Regional) to Brussels (BRU-Brussels - National) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Sioux Falls Regional
Destination airport
Brussels - National
Roundtrip price
$806
Distance
4387 mi

Book with confidence

Sioux Falls to Brussels Flights

The cheapest times to fly from Sioux Falls to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sioux Falls to Brussels are during the month of January. You can find some of the cheapest flights from Sioux Falls to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Sioux Falls to Brussels

Sunday is one of the best days to book for cheap flights from Sioux Falls to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Sioux Falls to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sioux Falls to Brussels in 2026. You can also book with separate airlines for your outbound and return journeys, from $357 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sioux Falls to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sioux Falls to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Sioux Falls to Brussels Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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