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$309 Cheap Flights from Sioux Falls (FSD) to Harrisburg (MDT)

View $309 flight on Sat, Oct 24, 2026Opens in a new window

Popular airlines from Sioux Falls Regional Airport (FSD) to Harrisburg Intl. Airport (MDT)

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Cheap Flights from Sioux Falls to Harrisburg (FSD-MDT)

Prices were available within the past 7 days and start at $309 for one-way flights and $321 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Oct 24 - Tue, Oct 27
FSD
Sioux Falls
MDT
Harrisburg
$321 Roundtrip, found 7 hours ago
$321
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Sat, Oct 24 from Sioux Falls to Harrisburg, returning Tue, Oct 27, priced at $321 found 7 hours ago
United
Sat, Oct 24 - Tue, Oct 27
FSD
Sioux Falls
MDT
Harrisburg
$321 Roundtrip, found 7 hours ago
$321
Roundtrip
found 7 hours ago
Select United flight, departing Sat, Oct 24 from Sioux Falls to Harrisburg, returning Tue, Oct 27, priced at $321 found 7 hours ago
American Airlines
Fri, Jan 29 - Tue, Feb 2
FSD
Sioux Falls
MDT
Harrisburg
$325 Roundtrip, found 8 hours ago
$325
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Fri, Jan 29 from Sioux Falls to Harrisburg, returning Tue, Feb 2, priced at $325 found 8 hours ago
United
Sat, Oct 24 - Tue, Oct 27
FSD
Sioux Falls
MDT
Harrisburg
$326 Roundtrip, found 7 hours ago
$326
Roundtrip
found 7 hours ago
Select United flight, departing Sat, Oct 24 from Sioux Falls to Harrisburg, returning Tue, Oct 27, priced at $326 found 7 hours ago
American Airlines
Thu, Dec 3 - Sun, Dec 6
FSD
Sioux Falls
MDT
Harrisburg
$329 Roundtrip, found 2 days ago
$329
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Dec 3 from Sioux Falls to Harrisburg, returning Sun, Dec 6, priced at $329 found 2 days ago
United
Sat, Oct 24 - Tue, Oct 27
FSD
Sioux Falls
MDT
Harrisburg
$354 Roundtrip, found 7 hours ago
$354
Roundtrip
found 7 hours ago
Select United flight, departing Sat, Oct 24 from Sioux Falls to Harrisburg, returning Tue, Oct 27, priced at $354 found 7 hours ago
United
Fri, Jan 29 - Tue, Feb 2
FSD
Sioux Falls
MDT
Harrisburg
$365 Roundtrip, found 8 hours ago
$365
Roundtrip
found 8 hours ago
Select United flight, departing Fri, Jan 29 from Sioux Falls to Harrisburg, returning Tue, Feb 2, priced at $365 found 8 hours ago
United
Sat, Oct 24 - Tue, Oct 27
FSD
Sioux Falls
MDT
Harrisburg
$370 Roundtrip, found 7 hours ago
$370
Roundtrip
found 7 hours ago
Select United flight, departing Sat, Oct 24 from Sioux Falls to Harrisburg, returning Tue, Oct 27, priced at $370 found 7 hours ago
United
Sat, Oct 24 - Tue, Oct 27
FSD
Sioux Falls
MDT
Harrisburg
$373 Roundtrip, found 7 hours ago
$373
Roundtrip
found 7 hours ago
Select United flight, departing Sat, Oct 24 from Sioux Falls to Harrisburg, returning Tue, Oct 27, priced at $373 found 7 hours ago
Delta
Sat, Oct 24 - Tue, Oct 27
FSD
Sioux Falls
MDT
Harrisburg
$449 Roundtrip, found 7 hours ago
$449
Roundtrip
found 7 hours ago
Select Delta flight, departing Sat, Oct 24 from Sioux Falls to Harrisburg, returning Tue, Oct 27, priced at $449 found 7 hours ago

Alternative airports near Harrisburg

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lancaster, PA LNS. Average driving time to city center is 48 minutes. Flights from $520
LNS
Lancaster, PA
Average driving time to city center48 min
Flights from $520

Find the cheapest month to fly from Sioux Falls (FSD) to Harrisburg (MDT)

January is typically the cheapest month to fly

From $258 - $694 per traveler.

What you need to know for your flight from Sioux Falls Regional to Harrisburg Intl.

Sioux Falls (FSD) to Harrisburg (MDT) at a glance

Travel from Sioux Falls (FSD) to Harrisburg (MDT) with a range of airlines offering convenient routes on this domestic short-haul journey. Search for Harrisburg flights to find the best options that align with your budget and schedule, including morning flights. Whether you’re eager to explore Harrisburg’s historic attractions or vibrant neighborhoods, you can easily discover the details for flights departing from Sioux Falls Regional Airport (FSD) to Harrisburg International Airport (MDT).

  • Fastest flight duration: around 3h 45m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 1,100 miles (1,770 km)
  • Flights per week: around 7 departures on average
  • Typical fares (one-way): economy tickets often range from $135–$485, depending on seasonality and how far ahead you book

Flights from Sioux Falls Regional Airport (FSD) to Harrisburg International Airport (MDT)

Based on the latest traveler bookings, here are the most popular airlines flying from Sioux Falls to Harrisburg, typically selected for their one-stop service. Common layover points include O'Hare International Airport (ORD) with about a 1-hour layover, Hartsfield-Jackson Atlanta International Airport (ATL) offering approximately 1 hour and 45 minutes, and Dallas-Fort Worth International Airport (DFW) with around a 3-hour and 15-minute layover. These options allow you to balance price, total travel time, and cabin class to create your ideal itinerary.

  • American Airlines: This full-service airline provides one-stop flights, with one-way prices generally between $140 and $525. It represents about 53% of the departures on this route, offering an in-flight duration of 3 hours and 45 minutes, leading to a total travel time of approximately 5 hours, including layover.
  • United: Offering a one-stop service, United Airlines has one-way fares that usually range from $135 to $420, accounting for roughly 38% of the route's departures. Passengers can expect an in-flight time of 3 hours and 45 minutes, with the complete journey taking around 5 hours, including a layover.
  • Delta: As another full-service option, Delta provides one-stop flights with one-way fares typically between $175 and $560. It makes up about 9% of the departures on this route, featuring an in-flight duration of 3 hours and 45 minutes and a total travel time of about 5 hours, including layover.

Alternative routes from Sioux Falls (FSD) to Harrisburg (MDT)

  • Sioux Falls to Harrisburg (FSD-HAR): Capital City Airport (HAR) lies approximately 5 miles from Harrisburg International Airport (MDT).
  • Sioux Falls to Lancaster (FSD-LNS): Lancaster Airport (LNS) is located about 25 miles from Harrisburg International Airport (MDT).
  • Sioux City to Harrisburg (SUX-MDT): Sioux Gateway Airport (SUX) is roughly 83 miles distant from Sioux Falls Regional Airport (FSD).

How to find the best prices for flights from Sioux Falls (FSD) to Harrisburg (MDT)

Getting some of the best deals on flights from Sioux Falls to Harrisburg is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are generally available when booking at least two months in advance, although many travelers book their flights two to eight weeks ahead. Departures in the afternoon, from 12 PM to 6 PM, often offer lower prices and are the most sought-after times. Additionally, flying on Thursday provides both better prices and is the most popular travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Harrisburg hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Harrisburg International Airport from Sioux Falls Regional Airport

Harrisburg welcomes travelers from Sioux Falls with a range of transport options based on price, convenience, and proximity. Harrisburg city center is approximately a 15-minute drive (covering about 12 miles) from Harrisburg International Airport, depending on traffic. Here's how to reach Harrisburg efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Harrisburg, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Harrisburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Harrisburg International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Harrisburg International Airport, Middletown Station, a train station, is located about 1.8 miles away by car.

Frequently asked questions

How much does a flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) cost?
You can find cheap one-way flights from $309 and cheap return flights from $321 Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) with Expedia. One-way flights typically cost between $270 and $1057, and return flights often range between $406 and $1699. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
The cheapest month to fly from FSD to MDT is October when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
Enter FSD to MDT and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Sioux Falls, SD (FSD) to Harrisburg, PA (MDT) with a layover in Dallas-Fort Worth Intl. (DFW), starting from around $729. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
To find a cheap flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
The earliest flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) typically departs at around 5:00 AM, operated by Delta. This seasonal service is active in March and April, allowing you to start your day early and arrive in Harrisburg with plenty of time to explore. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
The most popular departure times for flights from Sioux Falls Regional (FSD) to Harrisburg Intl. (MDT) are in the late morning, from 9am to 12pm. About 26% of passengers prefer this time window. Many major carriers, including United Airlines and Delta Airlines, offer flights during this window. This timing is favored because it allows travelers to arrive in Harrisburg with plenty of time to settle in for the day.
How long does it take to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
A flight from FSD to MDT with a layover takes around 4 hours 30 minutes, with the route covering approximately 1,051 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
You can fly first class between FSD and MDT. First class cabins are available on:

  • Delta Air Lines
  • United Airlines
  • American Airlines

How do I earn miles on a Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) flight with Expedia?
It's easy to earn miles on a Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Harrisburg from Sioux Falls Regional (FSD)?
If you're planning to travel to Harrisburg from Sioux Falls Regional (FSD), you can fly into Harrisburg Intl. (MDT) Some flights may connect through major hubs like Denver Intl. (DEN), Minneapolis - St. Paul Intl. (MSP), O'Hare Intl. (ORD) before reaching Harrisburg. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) at the last minute?
Typically, booking a last minute flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) flight and hotel package?
Securing a Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.)?
If you booked your Sioux Falls, SD (FSD-Sioux Falls Regional) to Harrisburg, PA (MDT-Harrisburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Sioux Falls Regional
Destination airport
Harrisburg Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$320
Distance
1050 mi

Book with confidence

Sioux Falls to Harrisburg Flights

The cheapest times to fly from Sioux Falls to Harrisburg

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sioux Falls to Harrisburg are during the month of October. You can find some of the cheapest flights from Sioux Falls to Harrisburg with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Sioux Falls to Harrisburg

Sunday is one of the best days to book for cheap flights from Sioux Falls to Harrisburg: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Sioux Falls to Harrisburg

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sioux Falls to Harrisburg in 2026. You can also book with separate airlines for your outbound and return journeys, from $309 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sioux Falls to Harrisburg flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sioux Falls to Harrisburg airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Sioux Falls to Harrisburg Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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