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$221 Cheap Flights from Greenville (GSP) to Harrisburg (MDT)

View $221 flight on Wed, Oct 7, 2026Opens in a new window

Popular airlines from Greenville-Spartanburg Intl. Airport (GSP) to Harrisburg Intl. Airport (MDT)

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Cheap Flights from Greenville to Harrisburg (GSP-MDT)

Prices were available within the past 7 days and start at $221 for one-way flights and $294 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Nov 25 - Thu, Nov 26
GSP
Greenville
MDT
Harrisburg
$294 Roundtrip, found 5 days ago
$294
Roundtrip
found 5 days ago
Select United flight, departing Wed, Nov 25 from Greenville to Harrisburg, returning Thu, Nov 26, priced at $294 found 5 days ago
American Airlines
Wed, Oct 7 - Sat, Oct 10
GSP
Greenville
MDT
Harrisburg
$299 Roundtrip, found 6 hours ago
$299
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Oct 7 from Greenville to Harrisburg, returning Sat, Oct 10, priced at $299 found 6 hours ago
United
Wed, Nov 25 - Thu, Nov 26
GSP
Greenville
MDT
Harrisburg
$312 Roundtrip, found 5 days ago
$312
Roundtrip
found 5 days ago
Select United flight, departing Wed, Nov 25 from Greenville to Harrisburg, returning Thu, Nov 26, priced at $312 found 5 days ago
American Airlines
Wed, Oct 7 - Sat, Oct 10
GSP
Greenville
MDT
Harrisburg
$314 Roundtrip, found 6 hours ago
$314
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Oct 7 from Greenville to Harrisburg, returning Sat, Oct 10, priced at $314 found 6 hours ago
Delta
Thu, Oct 8 - Sun, Oct 11
GSP
Greenville
MDT
Harrisburg
$319 Roundtrip, found 4 hours ago
$319
Roundtrip
found 4 hours ago
Select Delta flight, departing Thu, Oct 8 from Greenville to Harrisburg, returning Sun, Oct 11, priced at $319 found 4 hours ago
United
Wed, Nov 25 - Thu, Nov 26
GSP
Greenville
MDT
Harrisburg
$321 Roundtrip, found 5 days ago
$321
Roundtrip
found 5 days ago
Select United flight, departing Wed, Nov 25 from Greenville to Harrisburg, returning Thu, Nov 26, priced at $321 found 5 days ago
American Airlines
Thu, Oct 29 - Sun, Nov 1
GSP
Greenville
MDT
Harrisburg
$329 Roundtrip, found 4 days ago
$329
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Oct 29 from Greenville to Harrisburg, returning Sun, Nov 1, priced at $329 found 4 days ago
American Airlines
Wed, Oct 7 - Sat, Oct 10
GSP
Greenville
MDT
Harrisburg
$337 Roundtrip, found 6 hours ago
$337
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Oct 7 from Greenville to Harrisburg, returning Sat, Oct 10, priced at $337 found 6 hours ago
United
Sat, Oct 31 - Wed, Nov 4
GSP
Greenville
MDT
Harrisburg
$347 Roundtrip, found 11 hours ago
$347
Roundtrip
found 11 hours ago
Select United flight, departing Sat, Oct 31 from Greenville to Harrisburg, returning Wed, Nov 4, priced at $347 found 11 hours ago
Delta
Fri, Sep 25 - Tue, Sep 29
GSP
Greenville
MDT
Harrisburg
$349 Roundtrip, found 6 hours ago
$349
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Sep 25 from Greenville to Harrisburg, returning Tue, Sep 29, priced at $349 found 6 hours ago

Find the cheapest month to fly from Greenville (GSP) to Harrisburg (MDT)

January is typically the cheapest month to fly

From $228 - $408 per traveler.

What you need to know for your flight from Greenville-Spartanburg Intl. to Harrisburg Intl.

Greenville (GSP) to Harrisburg (MDT) at a glance

Travel from Greenville (GSP) to Harrisburg (MDT) with a selection of airlines catering to this domestic short-haul route. Explore various options, from full-service carriers to budget-friendly choices, to find the best fit for your schedule and wallet. Whether you're searching for cheap flights from Greenville or the cheapest flights to Harrisburg International Airport, you can easily gather the essential details for your journey from Greenville-Spartanburg International Airport to Harrisburg.

  • Fastest flight duration: around 2h 45m in-flight, plus roughly 1 hour layover with one stop
  • Route distance: roughly 450 miles (725 km)
  • Flights per week: around 9 departures on average
  • Typical fares (one-way): economy tickets often range from $115–$375, depending on seasonality and how far ahead you book

Flights from Greenville-Spartanburg International Airport (GSP) to Harrisburg International Airport (MDT)

Based on the latest traveler bookings, here are the top airlines flying from Greenville to Harrisburg, typically selected for their one-stop services. Popular layover choices include Philadelphia International Airport (PHL) with a layover of about 1 hour, Charlotte-Douglas International Airport (CLT) also offering around a 1-hour layover, and Washington Dulles International Airport (IAD), which has a similar layover duration. These options provide the flexibility to balance price, total travel time, and cabin class for the ideal itinerary.

  • American Airlines: This full-service airline provides one-stop travel options, with one-way ticket prices generally falling between $115 and $400. It represents about 57% of the flights on this route, featuring an in-flight duration of 2 hours and 45 minutes, while the total travel time, including layover, is around 4 hours.
  • Delta: As another full-service carrier, Delta offers one-stop services with one-way fares ranging from $115 to $365. It makes up roughly 24% of the departures on this route. Passengers can expect an in-flight time of 2 hours and 45 minutes, with a combined journey time of about 4 hours, including layover.
  • United: United Airlines is a full-service airline that provides one-stop flights, with one-way fares typically between $115 and $330. It accounts for approximately 19% of the departures for this route. The in-flight duration is 2 hours and 45 minutes, culminating in a total travel time of about 4 hours when factoring in layover.

Best time to fly from Greenville (GSP) to Harrisburg (MDT)

The most popular months for travelers flying from Greenville to Harrisburg are January, March, and May, when peak temperatures in Harrisburg reach up to 61.3°F in May. If you prefer quieter travel, consider July, the least busy time to visit with temperatures around 75.2°F and typically the lowest average one-way fare (around $183). Flight availability peaks in May, with approximately 10 flights per week, making it easier to find convenient departure times. April has the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: July usually offers good deals with average one-way fare around $183, roughly 14% cheaper than the yearly average.
  • More budget-friendly months to fly: April and May typically offer average one-way fares of around $196.
  • Most flight options: May has the highest number of flights from Greenville to Harrisburg, with approximately 10 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January29.8°F (-1.2°C)Moderately High8$236
February32.2°F (0.1°C)Average9$221
March40.3°F (4.6°C)Moderately High9$215
April51.3°F (10.7°C)Average7$192
May61.3°F (16.3°C)Moderately High10$200
June69.6°F (20.9°C)Average9$206
July75.2°F (24.0°C)Moderately Low8$183
August72.9°F (22.7°C)Average9$204
September66.2°F (19.0°C)Average9$251
October55.0°F (12.8°C)Average9$207
November42.8°F (6.0°C)Moderately Low8$222
December35.6°F (2.0°C)Moderately Low8$220

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Greenville (GSP) to Harrisburg (MDT)

  • Greenville to Harrisburg (GSP-HAR): Capital City Airport (HAR) lies approximately 5 miles from Harrisburg International Airport (MDT).
  • Spartanburg to Harrisburg (SPA-MDT): Spartanburg Downtown Memorial Airport (SPA) is located roughly 15 miles from Greenville-Spartanburg International Airport (GSP).
  • Greenville to Lancaster (GSP-LNS): Lancaster Airport (LNS) is about 25 miles distant from Harrisburg International Airport (MDT).

How to find the best prices for flights from Greenville (GSP) to Harrisburg (MDT)

Getting some of the best deals on flights from Greenville to Harrisburg is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Morning departures between 5 a.m. and 12 p.m. tend to be the most affordable and are also popular time slots. Additionally, flying on Saturday often provides lower prices, even though Friday is the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Harrisburg hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Harrisburg International Airport from Greenville-Spartanburg International Airport

Harrisburg welcomes travelers from Greenville with a range of transport options based on price, convenience, and proximity. For departures, Greenville-Spartanburg International Airport is roughly a 20-minute drive (covering about 16 miles) from central Greenville. Harrisburg city center is approximately a 15-minute drive (covering about 12 miles) from Harrisburg International Airport, depending on traffic. Here's how to reach Harrisburg efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Harrisburg, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Harrisburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Harrisburg International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Harrisburg International Airport, Middletown Station, a train station, is located about 1.8 miles away by car.

Frequently asked questions

How much does a flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) cost?
You can find cheap one-way flights from $221 and cheap return flights from $294 Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) with Expedia. One-way flights generally range between $193 and $660, and roundtrip flights usually range from $382 to $1051. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.)?
The cheapest month to fly from GSP to MDT is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.)?
Enter GSP to MDT and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.)?
To find a cheap flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.)?
The earliest flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) typically leaves at around 5:00 AM local time, operated by American Airlines. This seasonal service is available in October, allowing you to maximize your time in Harrisburg. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.)?
The most popular departure times for flights from Greenville-Spartanburg Intl. (GSP) to Harrisburg Intl. (MDT) are in the early morning, from 6am to 9am. About 31% of passengers prefer this time window. Many major carriers, including American Airlines, Delta, and United Airlines, offer flights during this window. This timing is favored because it lets you arrive in Harrisburg with plenty of time to start your day.
How long does it take to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.)?
Flights from GSP to MDT with one stop typically take around 3 hours 50 minutes, covering approximately 473 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.)?
You can fly first class between GSP and MDT. First class cabins are available on:

  • United Airlines
  • American Airlines
  • Delta Air Lines

How do I earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) flight with Expedia?
It's easy to earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Harrisburg from Greenville-Spartanburg Intl. (GSP)?
From Greenville-Spartanburg Intl. (GSP), you can fly into Harrisburg Intl. (MDT) to reach Harrisburg. Some flights may connect through major hubs like Liberty Intl. (EWR), O'Hare Intl. (ORD), Charlotte-Douglas Intl. (CLT) before reaching Harrisburg. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) at the last minute?
Typically, booking a last minute flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) flight and hotel package?
Securing a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.)?
If you booked your Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Harrisburg, PA (MDT-Harrisburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Greenville-Spartanburg Intl.
Destination airport
Harrisburg Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$294
Distance
472 mi

Book with confidence

Greenville to Harrisburg Flights

The cheapest times to fly from Greenville to Harrisburg

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Greenville to Harrisburg are during the month of November. You can find some of the cheapest flights from Greenville to Harrisburg with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Greenville to Harrisburg

Sunday is one of the best days to book for cheap flights from Greenville to Harrisburg: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Greenville to Harrisburg

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Greenville to Harrisburg in 2026. You can also book with separate airlines for your outbound and return journeys, from $221 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Greenville to Harrisburg flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Greenville to Harrisburg airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Greenville to Harrisburg Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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