$439 Cheap Flights from Guayaquil (GYE) to Greenville (GSP)

View $439 flight on Sun, Feb 1, 2026Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP)

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Cheap Flights from Guayaquil to Greenville (GYE-GSP)

Prices were available within the past 7 days and start at $439 for one-way flights and $616 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Sat, May 9 - Sun, May 24
GYE
Guayaquil
GSP
Greenville
$616 Roundtrip, found 4 days ago
$616
Roundtrip
found 4 days ago
Select avianca flight, departing Sat, May 9 from Guayaquil to Greenville, returning Sun, May 24, priced at $616 found 4 days ago
United
Fri, May 8 - Sat, May 23
GYE
Guayaquil
GSP
Greenville
$617 Roundtrip, found 4 days ago
$617
Roundtrip
found 4 days ago
Select United flight, departing Fri, May 8 from Guayaquil to Greenville, returning Sat, May 23, priced at $617 found 4 days ago
avianca
Sun, May 10 - Sat, May 23
GYE
Guayaquil
GSP
Greenville
$624 Roundtrip, found 4 days ago
$624
Roundtrip
found 4 days ago
Select avianca flight, departing Sun, May 10 from Guayaquil to Greenville, returning Sat, May 23, priced at $624 found 4 days ago
United
Fri, May 8 - Sun, May 24
GYE
Guayaquil
GSP
Greenville
$626 Roundtrip, found 4 days ago
$626
Roundtrip
found 4 days ago
Select United flight, departing Fri, May 8 from Guayaquil to Greenville, returning Sun, May 24, priced at $626 found 4 days ago
United
Mon, Apr 27 - Tue, May 12
GYE
Guayaquil
GSP
Greenville
$632 Roundtrip, found 5 days ago
$632
Roundtrip
found 5 days ago
Select United flight, departing Mon, Apr 27 from Guayaquil to Greenville, returning Tue, May 12, priced at $632 found 5 days ago
United
Wed, Jan 21 - Tue, Apr 21
GYE
Guayaquil
GSP
Greenville
$633 Roundtrip, found 3 days ago
$633
Roundtrip
found 3 days ago
Select United flight, departing Wed, Jan 21 from Guayaquil to Greenville, returning Tue, Apr 21, priced at $633 found 3 days ago
United
Wed, Jan 21 - Sat, Apr 18
GYE
Guayaquil
GSP
Greenville
$635 Roundtrip, found 3 days ago
$635
Roundtrip
found 3 days ago
Select United flight, departing Wed, Jan 21 from Guayaquil to Greenville, returning Sat, Apr 18, priced at $635 found 3 days ago
Copa
Fri, May 8 - Sun, May 24
GYE
Guayaquil
GSP
Greenville
$644 Roundtrip, found 4 days ago
$644
Roundtrip
found 4 days ago
Select Copa flight, departing Fri, May 8 from Guayaquil to Greenville, returning Sun, May 24, priced at $644 found 4 days ago
Delta
Mon, May 11 - Tue, May 26
GYE
Guayaquil
GSP
Greenville
$676 Roundtrip, found 4 days ago
$676
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, May 11 from Guayaquil to Greenville, returning Tue, May 26, priced at $676 found 4 days ago
American Airlines
Sun, May 10 - Wed, Jun 10
GYE
Guayaquil
GSP
Greenville
$684 Roundtrip, found 4 days ago
$684
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, May 10 from Guayaquil to Greenville, returning Wed, Jun 10, priced at $684 found 4 days ago

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $1,084
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $1,084
Flights from Guayaquil (GYE) to Greenville (GSP)
Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, LATAM Airlines Group, United
Roundtrip price
$615
Distance
2563 mi

Guayaquil to Greenville Flights

The cheapest times to fly from Guayaquil to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Guayaquil to Greenville are during the month of May. You can find some of the cheapest flights from Guayaquil to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Guayaquil to Greenville

Sunday is one of the best days to book for cheap flights from Guayaquil to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Guayaquil to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Guayaquil to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $439 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Guayaquil to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Guayaquil to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Get a cheap one-way flight from $439 or cheap return flight from $616 from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP)?
May is the most affordable month to fly from GYE to GSP. Traveling outside of peak seasons is often the key to finding better deals on flights.
What is the cheapest airline that flies from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP)?
To find the cheapest airline flying from GYE to GSP, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP)?
You'll need to take a flight with a layover when traveling from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from GYE to GSP?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP)?
To arrive at Greenville-Spartanburg Intl. Airport (GSP) on schedule, choose a flight that leaves from Jose Joaquin de Olmedo Intl. Airport (GYE) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Last-minute fares from GYE to GSP are generally more expensive. To lock in the lowest prices, start looking for flights as soon as possible. That said, if you're flexible with your travel dates, you may land a cheap ticket right before your journey.
Is it cheaper to book a GYE to GSP flight and hotel package?
Compared with arranging hotels and flights separately, booking a GYE to GSP flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one convenient place takes the hassle out of travel planning. Simply secure your flights and choose from our wide range of hotels, then customize your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Greenville-Spartanburg Intl. Airport (GSP)?
Usually, it's possible to cancel or reschedule your GYE to GSP flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.