$554 Cheap Flights from Houston (HOU) to Santander (SDR)

View $554 flight on Sat, Nov 22, 2025Opens in a new window

Popular airlines from Houston William Hobby Airport (HOU) to Santander (SDR)

Cheap Flights from Houston to Santander (HOU-SDR)

Prices were available within the past 7 days and start at $554 for one-way flights and $903 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Wed, May 20 - Thu, Jun 4
HOU
Houston
SDR
Santander
$903 Roundtrip, found 5 days ago
$903
Roundtrip
found 5 days ago
Select Iberia flight, departing Wed, May 20 from Houston to Santander, returning Thu, Jun 4, priced at $903 found 5 days ago

Frequently asked questions

How much does a flight from William P. Hobby Airport (HOU) to Santander Airport (SDR) cost?
Grab a cheap one-way flight from $554 or cheap return flight from $903 from William P. Hobby Airport (HOU) to Santander Airport (SDR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from William P. Hobby Airport (HOU) to Santander Airport (SDR)?
The cheapest month to fly from HOU to SDR is May, when there's less demand. Off-peak season is usually when better flight deals are available between these airports.
What is the cheapest airline that flies from William P. Hobby Airport (HOU) to Santander Airport (SDR)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll take you from HOU to SDR. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from William P. Hobby Airport (HOU) to Santander Airport (SDR)?
There are no daily nonstop flights from William P. Hobby Airport (HOU) to Santander Airport (SDR). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from HOU to SDR?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a number of factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from William P. Hobby Airport (HOU) to Santander Airport (SDR)?
To land at Santander Airport (SDR) without delays, opt for a flight that leaves from William P. Hobby Airport (HOU) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from William P. Hobby Airport (HOU) to Santander Airport (SDR) last-minute?
Waiting until just before your departure to book your flight from HOU to SDR generally means paying more. While it's possible to find some last-minute discounts, there's no guarantee. Be flexible with your itinerary for the best chance of scoring a bargain.
Is it cheaper to book a HOU to SDR flight and hotel package?
Securing a HOU to SDR flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Select from our extensive range of hotels and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from William P. Hobby Airport (HOU) to Santander Airport (SDR)?
Typically, you can cancel or modify your HOU to SDR flight. However, additional charges may apply, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you want further details, go to our Customer Service portal.

Travel information

Travel information

Origin airport
William P. Hobby
Destination airport
Santander
Roundtrip price
$902
Distance
4911 mi

Book with confidence

Book with confidence

Houston to Santander Flights

The cheapest times to fly from Houston to Santander

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Houston to Santander are during the month of May. You can find some of the cheapest flights from Houston to Santander with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Houston to Santander

Sunday is one of the best days to book for cheap flights from Houston to Santander: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Houston to Santander

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Houston to Santander in 2025. You can also book with separate airlines for your outbound and return journeys, from $554 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Houston to Santander flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Houston to Santander airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Houston to Santander Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.