$150 Cheap Flights from Islip (ISP) to Santo Domingo (SDQ)

View $150 flight on Tue, Nov 18, 2025Opens in a new window

Popular airlines from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ)

Cheap Flights from Islip to Santo Domingo (ISP-SDQ)

Prices were available within the past 7 days and start at $150 for one-way flights and $324 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Tue, Nov 18 - Wed, Nov 26
ISP
Islip
SDQ
Santo Domingo
$324 Roundtrip, found 1 day ago
$324
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Tue, Nov 18 from Islip to Santo Domingo, returning Wed, Nov 26, priced at $324 found 1 day ago
JetBlue Airways
Sun, Nov 23 - Fri, Dec 5
ISP
Islip
SDQ
Santo Domingo
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Sun, Nov 23 from Islip to Santo Domingo, returning Fri, Dec 5, priced at $349 found 1 day ago
JetBlue Airways
Sun, Nov 23 - Sun, Dec 7
ISP
Islip
SDQ
Santo Domingo
$362 Roundtrip, found 1 day ago
$362
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Sun, Nov 23 from Islip to Santo Domingo, returning Sun, Dec 7, priced at $362 found 1 day ago
JetBlue Airways
Wed, Nov 12 - Tue, Dec 2
ISP
Islip
SDQ
Santo Domingo
$364 Roundtrip, found 1 day ago
$364
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Wed, Nov 12 from Islip to Santo Domingo, returning Tue, Dec 2, priced at $364 found 1 day ago
JetBlue Airways
Tue, Nov 18 - Thu, Nov 27
ISP
Islip
SDQ
Santo Domingo
$369 Roundtrip, found 1 day ago
$369
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Tue, Nov 18 from Islip to Santo Domingo, returning Thu, Nov 27, priced at $369 found 1 day ago
JetBlue Airways
Sun, Dec 7 - Tue, Dec 16
ISP
Islip
SDQ
Santo Domingo
$376 Roundtrip, found 1 day ago
$376
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Sun, Dec 7 from Islip to Santo Domingo, returning Tue, Dec 16, priced at $376 found 1 day ago
JetBlue Airways
Mon, Nov 17 - Wed, Nov 26
ISP
Islip
SDQ
Santo Domingo
$381 Roundtrip, found 1 day ago
$381
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Mon, Nov 17 from Islip to Santo Domingo, returning Wed, Nov 26, priced at $381 found 1 day ago
JetBlue Airways
Tue, Dec 9 - Wed, Dec 24
ISP
Islip
SDQ
Santo Domingo
$383 Roundtrip, found 1 day ago
$383
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Tue, Dec 9 from Islip to Santo Domingo, returning Wed, Dec 24, priced at $383 found 1 day ago
JetBlue Airways
Tue, Dec 9 - Thu, Dec 25
ISP
Islip
SDQ
Santo Domingo
$385 Roundtrip, found 1 day ago
$385
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Tue, Dec 9 from Islip to Santo Domingo, returning Thu, Dec 25, priced at $385 found 1 day ago
Frontier Airlines
Wed, Feb 18 - Sat, Feb 28
ISP
Islip
SDQ
Santo Domingo
$429 Roundtrip, found 1 day ago
$429
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Feb 18 from Islip to Santo Domingo, returning Sat, Feb 28, priced at $429 found 1 day ago

Alternative airports near Santo Domingo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $429
SDQ
Las Americas Intl.
Cheapest
Average driving time to city center22 min
Flights from $429

Frequently asked questions

How much does a flight from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ) cost?
Snag a cheap one-way flight from $150 or cheap return flight from $324 from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ)?
The cheapest month to fly from ISP to SDQ is November, when there's less demand. Off-peak months are generally when airlines offer lower prices between these airports.
Which airlines fly direct from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ)?
Although Islip, NY (ISP-MacArthur) doesn't offer any direct flights to Las Americas Intl. Airport (SDQ), other airports have nonstop routes. Taking off from John F. Kennedy Intl. Airport (JFK) will get you to Santo Domingo without any detours.
What is the cheapest airline that flies from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ)?
To find the cheapest airline that'll fly you from ISP to SDQ, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ)?
There are no daily nonstop flights departing from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ). But you can book flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from ISP to SDQ?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can vary depending on various factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ)?
To avoid potential delays on the MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ) last-minute?
Last-minute fares from ISP to SDQ are usually more expensive. To lock in the lowest rates, start searching for flights early. That said, if you can play around with your travel dates, you may land a cheap ticket right before your journey.
Is it cheaper to book an ISP to SDQ flight and hotel package?
Compared with arranging flights and hotels separately, booking an ISP to SDQ flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one convenient place will take the hassle out of travel planning. Simply pick your flights and choose from our wide range of hotels, then personalize your trip with extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ)?
If you reserved your ISP to SDQ flight within the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you want more information.

Travel information

Origin airport
MacArthur
Destination airport
Las Americas Intl.
Airlines serving
Frontier Airlines, JetBlue Airways
Roundtrip price
$323
Distance
1557 mi

Book with confidence

Islip to Santo Domingo Flights

The cheapest times to fly from Islip to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Islip to Santo Domingo are during the month of November. You can find some of the cheapest flights from Islip to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Islip to Santo Domingo

Sunday is one of the best days to book for cheap flights from Islip to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Islip to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Islip to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $150 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Islip to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Islip to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Islip to Santo Domingo Flights

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*Available to One Key members.